40 Years of Visionary Innovation at the USC Roski Eye Institute

1978
Developed a laboratory model of penetrating eye injuries that influences the management of trauma in humans
1979
Developed a laboratory model of choroidal neovascularization now widely used to study pathogenesis and treatment of subretinal neovascularization
1987
Implanted the first artificial cornea in a pediatric patient
Identified the gene that causes retinoblastoma
1991
Pioneered Optical Coherence Tomography (OCT)
1992
Addressed vision complications from AIDS by diagnosing and developing treatments for opportunistic eye infections and Kaposi’s sarcoma
1998
Developed the Baerveldt® glaucoma implant for preserving vision in glaucoma patients by reducing eye pressure
1999
Developed a noninvasive glucose-monitoring system using Raman spectrum signals from the aqueous
2000
Began the Los Angeles Latino Eye Study, the world’s largest investigation into eye disease in Latinos
2002
Implanted the first artificial retina in a patient after beginning collaboration with the U.S. Department of Energy Office of Science in 1999
2005
Pioneered use of ultra-high speed Fournier domain optical coherence tomography (OCT) to improve glaucoma diagnosis
2009
Identified the unique mechanism of uptake in lacrimal gland for adenovirus 5 that may facilitate drug delivery
2010
Developed a Web-accessible visual field test and analysis system for multicenter studies and touchpad device access
2011
Began first clinical trials for an experimental therapeutic agent to treat Leber’s Hereditary Optic Neuropathy, a mitochondrial disease
2013
Received Argus II Retinal Prosthesis System approval by the United States Food and Drug Administration for patients with retinitis pigmentosa
2014
Discovered which retinal cells mutate to become retinoblastoma.

Implanted a programmable micropump smart device that delivers precise small doses of medications into the eyes of patients with diabetic macular edema, in the first-in-man clinical trial
2015
Pioneered use of OCT Angiography for diagnosis and management of retinal vascular diseases. USC Roski Eye Institute, was one of two research sites to conduct preclinical pilot studies using prototype OCT Angiography devices which was FDA approved for clinical use.

USC Roski Eye Institute Patient Becomes First Blind Patient to have Two artificial retinal prostheses, Argus I and newest generation of Argus II –one in each eye
2016
Longtime USC benefactors Gayle and Edward Roski have made a landmark $25 million gift to endow and name the USC Gayle and Edward Roski Eye Institute

Dr. Mark Humayun honored by President Barack Obama with the National Medal of Technology and Innovation

Two FDA-approvals this year- corneal cross-linking (CXL), an innovative procedure that provides effective treatment for keratoconus, and the XEN Glaucoma Treatment System, which reduces intraocular pressure with a tiny flexible stent that is implanted using an injector applicator
2017
California’s first certified ophthalmic education program, one of only 13 in the nation, debuts at USC Roski Eye Institute

Visionary Care, Research & Education

Are you in search of eye care that will not only address your pressing health concerns, but set a path for you to reach a happier and healthier everyday life? The USC Roski Eye Institute has been providing cutting-edge eye care for over 40 years and treats hundreds of patients on a daily basis. By providing ophthalmology treatments that are tailored to each patient’s unique needs, you can rest assured that you will receive both the time and care that you deserve for your condition.

USC Roski Eye InstituteBecause of our commitment to high quality eye care, the USC Roski Eye Institute has consistently ranked in the top 10 for ophthalmology programs in publications such as U.S. News and World Report and Ophthalmology Times. We are also one of the top federally funded institutes in the world. This funding means that we have an unparalleled ability to delve into groundbreaking research across the field of ophthalmology.

With locations in Los Angeles, Beverly Hills, Arcadia, and Pasadena, we are able to provide timely treatments for patients across southern California. Whether you are looking for an assessment of minor eyesight problems or help with life-changing ophthalmic conditions, our specialized eye care team has the insight and expertise that you need. To speak with our ophthalmology team, learn more about our treatment options, and schedule an appointment, call 323-442-6335 or fill out our online contact form.

An Inside Look at USC Roski Eye Institute

In 1974, USC Keck School of Medicine established the USC Department of Ophthalmology, which grew into the USC Roski Eye Institute and became an essential regional, national and global leader in the field. The USC Roski Eye Institute has more than 135 faculty covering all subspecialties of ophthalmology. In addition to the Top 10 ranking by U.S. News & World Report for 21 years, the USC Department of Ophthalmology is No. 2 in research funding from the National Eye Institute. Over the past four decades, USC Roski Eye Institute faculty members have received international acclaim for their contributions to vision research, including the development of optical coherence tomography (OCT) and OCT angiography, a non-invasive imaging technique used to diagnose glaucoma, diabetic eye disease, macular degeneration and other retinal and optic nerve disorders, the Baerveldt glaucoma implant, the world’s most widely used glaucoma implant and the XEN implant – the most effective minimally invasive glaucoma surgery. USC Roski Eye Institute physician scientists developed the only commercially available retinal prosthesis, Argus II Retinal Prosthesis System, to restore vision to those blind from retinitis pigmentosa and a long-term ocular drug delivery pump for the treatment of diabetic eye disease and macular degeneration. Currently, the USC Roski Eye Institute is one of the few centers enrolling patients for stem cell-based treatments for macular degeneration. The USC Roski Eye Institute also is one of the leading eye centers in the world studying the burden of vision loss and its impact on quality of life among vulnerable populations such as children and minorities.

To learn more about the most recent developments at the USC Roski Eye Institute, read our Annual ReportFall UpClose Newsletter, and the latest USC ophthalmology news.

Our most recent major breakthroughs include the following:

  • Debuting California’s first certified ophthalmic education program, one of only 13 in the nation
  • Leading NEI eye disease research among multi-ethnic populations
  • Inventing the FDA-approved XEN stent, the most widely used glaucoma implant in the world
  • Changing health care policy in the United States – our world-renowned population-based health studies have led to new treatment and prevention initiatives
  • Leading researchers of eye disease prevention and treatment as part of the Human Connectome brain mapping research
  • Pioneering use of ultra-high speed Fourier domain optical coherence tomography (OCT) – revolutionized how ophthalmologists diagnose diseases of the eye
  • Inventing the world’s first FDA-approved artificial retina, Argus II – this device has brought an unprecedented degree of sight back to those blinded by retinitis pigmentosa
  • Developing a new stem cell therapy for age-related macular degeneration
  • Discovering the mutation in retinal cells that causes retinoblastomas – the most common type of eye cancer in children
  • Pioneered use of OCT Angiography for diagnosis and management of retinal vascular diseases. USC Roski Eye Institute, was one of two research sites to conduct preclinical pilot studies using prototype OCT Angiography devices which was FDA approved for clinical use
  • USC Roski Eye Institute Patient Becomes First Blind Patient to have Two artificial retinal prostheses, Argus I and newest generation of Argus II –one in each eye

These breakthroughs offer hope to those suffering from vision loss and allow patients access to cutting-edge care.

Next, read about our residency and fellowship.

Research Opportunities

At the USC Roski Eye Institute, we provide an interdisciplinary approach that allows for collaboration between departments and leads to some of the most important cutting edge research both locally and internationally. Some of the fields of study currently making important strides in the world of eye care include biomedical engineering, from which artificial retinas and long term drug delivery implants have been created, and stem cell research to treat and prevent macular degeneration. We also collaborate with the USC Institute of Neuroimaging and Informatics, which allows for imaging of the eye and brain in order to develop early detection of eye diseases.

The USC Roski Eye Institute is not only one of the leading eye centers in the nation, but is home to cutting edge ophthalmology treatments that revolutionize ophthalmology across the world.. From medical students to fellows, we are dedicated to providing the best, most comprehensive, and most supportive research and training environment. Our faculty are hands-on, caring, and knowledgeable, and will not hesitate to provide support and guidance through your entire time in the program. We are part of the Keck School of Medicine of USC, and offer interdisciplinary studies integrating different fields in an exciting and innovative manner.

In addition, our Pediatric Ophthalmology Service has the distinction of being the only program in the country to offer almost every pediatric ophthalmology subspecialty in existence. We partner with the Children’s Hospital of Los Angeles to provide hands-on training and opportunities for interaction with and observation of pediatric ophthalmology patients, researchers, and doctors.

Trailblazers in Ophthalmology

The USC Roski Eye Institute is recognized as a leader in patient care, vision research, and physician training. You can expect high-level diagnostics, treatments, and preventative care for your unique needs and our ophthalmology team strives to improve our patients’ lives through the most advanced treatments available. Our history of success in the field of ophthalmology has led the USC Roski Eye Institute to be recognized through many accolades and awards, including:

Are you interested in learning more about how we can help you find the eye care you or a loved one deserves? Get in touch with us today by calling 323-745-2223 today or filling out our online contact form. A better and brighter future is possible with the USC Roski Eye Institute.