DoctorsA. Linn Murphree, MD

A. Linn Murphree, MD

Title: Clinical Professor of Ophthalmology and Co-Director of the Retinoblastoma Program at Children's Hospital Los Angeles (CHLA)

Department: Ophthalmology

Clinical Specialty: Vitreoretinal Surgery and Retinal Disease

Treatment Expertise: Retinal Diseases, Retinopathy of Prematurity (ROP), Pediatric Ophthalmology

Certification: American Board of Ophthalmology

Language: English

Location: Children’s Hospital Los Angeles

Biography and Education

Biography

A. Linn Murphee, MD, graduated from Baylor College of Medicine with a medical degree in 1972. He completed a residency in ophthalmology and fellowship in medical genetics at the Methodist, Ben Taub, Veterans and Texas Children’s Hospital. Dr. Murphee then attended the prestigious Wilmer Eye Institute, Johns Hopkins University Hospital, for fellowship training in ophthalmic genetics and pediatrics. Dr. Murphee has also been recognized by the U.S. News & World Report Best Doctor’s List. Dr. Murphree is a professor of Ophthalmology and Pediatrics at the University of Southern California, Keck School of Medicine, and the co-director of the Retinoblastoma Program at Children’s Hospital Los Angeles. He established the retinoblastoma referral center at Children’s Hospital Los Angeles more than thirty years ago. Today it is a global resource for physicians and families.

Research Interests:

Dr. Murphree has devoted his professional career to increase our understanding of retinoblastoma and caring for children with childhood eye cancer. He has been instrumental in identifying the genetic mutation causing retinoblastoma and has recently developed a new classification system to describe the disease.

Education

  • MD, Baylor College of Medicine, Houston, Texas, 1972

Internship

  • Baylor College of Medicine, Affiliated Hospitals

Residency

  • Methodist, Ben Taub, Veterans and Texas Children’s Hospital, Houston, Texas, 1976

Fellowship

  • Methodist, Ben Taub, Veterans and Texas Children’s Hospital, Houston, Texas, 1973
  • The Wilmer Eye Institute, Johns Hopkins University Hospital, Baltimore, MD, 1977

Textbook

Clinical Ophthalmic Oncology

Accomplishments

Professional society memberships

  • Los Angeles Pediatric Society
  • Louisiana-Mississippi Ophthalmological and Otolaryngological Society (Honorary Fellowship)
  • Ophthalmology Research Study Club of Los Angeles
  • Pacific Coast Oto-Ophthalmological Society
  • Salerni Collegium
  • American Academy of Ophthalmology
  • American Academy of Pediatrics (Ophthalmology Specialty Fellowship)
  • American Association for Pediatric Ophthalmology and Strabismus
  • American Medical Association
  • American Orthoptic Council
  • American Telemedicine Association
  • Association for Research in Vision and Ophthalmology
  • Baylor Ophthalmology Residents Alumni Association
  • Johns Hopkins University Alumni Association
  • Ophthalmic Genetics Study Club
  • Society of Heed Fellows
  • Wilmer Residents Association
  • International Society for Eye Research
  • International Society of Genetic Eye Disease
  • Pan American Association of Ophthalmology

Awards

  • Franceschetti Gold Medal recipient, Sienna, Italy. VI International Symposium on Retinoblastoma, 1992
  • The American Association for Pediatric Ophthalmology and Strabismus Honor Award, 1992
  • Research to Prevent Blindness Senior Scientific Investigators Award recipient, 1993
  • Invited Lecturer on Retinoblastoma, Russian Federation of Head and Neck Cancer, Moscow, October, 1993
  • The Morris & Mary Press Humanism Award, 1994
  • Heed Award, Society of Heed Fellows, October, 1995
  • Heed Fellowship, Harvard Medical School 1996 Resident Teaching Award, Weill Medical College, Cornell University, 1996
  • Distinguished House Staff Award, Society of the New York-Presbyterian Hospital 1996 Keynote Lecturer, International
  • Symposium on Ocular Tumors, Jerusalem, Israel 1997 Senior Honor Award Recipient, American Academy of Ophthalmology
  • 1997 Recipient of the Sheen Award, American College of Surgeons and Fleet Bank 1997 U.S. News & World Report Best
  • Doctor’s List 1998-2001 Keynote Lecturer on Retinoblastoma, European Ophthalmic Congress, Istanbul, Turkey, 2001
  • Proctor/Lecturer: University of California at San Francisco, 2001 Invited to Deliver the 2010 Costenbader Lecture at the 2010
  • AAPOS Meeting

Publications

  1. Berry JL, Shih G, Moysidis SN, Jubran R, Wong K, Lee TC, Murphree AL, Kim JW. Patterns of Subretinal Fluid Resolution in Group D Eyes Treated with Chemoreduction: Experience from the Children’s Hospital Los Angeles/University of Southern California. Ophthalmic Genet. 2016 Mar 2:1-4.
  2. Zhu D, Berry JL, Ediriwickrema L, Wong K, Lee TC, Murphree AL, Kim JW, Jubran R. Long-Term Outcomes of Group B Eyes in Patients with Retinoblastoma Treated with Short-Course Chemoreduction: Experience from Children’s Hospital Los Angeles/University of Southern California. Ocul Oncol Pathol. 2015 Dec;2(2):105-11.
  3. Browne AW, Dandapani SV, Jennelle R, Stevanovic M, Lee TC, Murphree AL, et al. Outcomes of medium choroidal melanomas treated with ruthenium brachytherapy guided by three-dimensional pretreatment modeling. Brachytherapy. 2015;14(5):718-25. Epub 2015/06/16. doi: 10.1016/j.brachy.2015.04.010. PubMed PMID: 26073224.
  4. Kim JW, Ngai LK, Sadda S, Murakami Y, Lee DK, Murphree AL. Retcam fluorescein angiography findings in eyes with advanced retinoblastoma. The British journal of ophthalmology. 2014;98(12):1666-71. Epub 2014/07/24. doi: 10.1136/bjophthalmol-2014-305180. PubMed PMID: 25053763.
  5. Berry JL, Jubran R, Wong K, Lee TC, Murphree AL, Kim JW. Factors predictive of long-term visual outcomes of Group D eyes treated with chemoreduction and low-dose IMRT salvage: the Children’s Hospital Los Angeles experience. The British journal of ophthalmology. 2014;98(8):1061-5. Epub 2014/03/29. doi: 10.1136/bjophthalmol-2013-304411. PubMed PMID: 24671926.
  6. Earl JB, Minckler DS, Lee TC, Murphree AL. Malignant teratoid medulloepithelioma with retinoblastic and rhabdomyoblastic differentiation. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus. 2013;17(3):328-31. Epub 2013/06/26. doi: 10.1016/j.jaapos.2013.02.005. PubMed PMID: 23791415.
  7. Paquette LB, Miller D, Jackson HA, Lee T, Randolph L, Murphree AL, et al. In utero detection of retinoblastoma with fetal magnetic resonance and ultrasound: initial experience. AJP reports. 2012;2(1):55-62. Epub 2013/08/16. doi: 10.1055/s-0032-1316465. PubMed PMID: 23946908; PubMed Central PMCID: PMCPmc3653521.
  8. Murphree AL, Triche TJ. An epigenomic mechanism in retinoblastoma: the end of the story? Genome medicine. 2012;4(2):15. Epub 2012/03/01. doi: 10.1186/gm314. PubMed PMID: 22364211; PubMed Central PMCID: PMCPmc3392761.
  9. Lee NG, Berry JL, Lee TC, Wang AT, Honowitz S, Murphree AL, et al. Sonoporation enhances chemotherapeutic efficacy in retinoblastoma cells in vitro. Investigative ophthalmology & visual science. 2011;52(6):3868-73. Epub 2011/01/29. doi: 10.1167/iovs.10-6501. PubMed PMID: 21273549; PubMed Central PMCID: PMCPmc3109062.
  10. Lam HD, Samuel MA, Rao NA, Murphree AL. Retinoblastoma presenting as Coats’ disease. Eye (London, England). 2008;22(9):1196-7. Epub 2007/12/01. doi: 10.1038/sj.eye.6703046. PubMed PMID: 18049483.
  11. Kase S, Parikh JG, Youssef PN, Murphree AL, Rao NA. Transforming growth factor beta in retinoblastoma-related cataract. Archives of ophthalmology (Chicago, Ill : 1960). 2008;126(11):1539-42. Epub 2008/11/13. doi: 10.1001/archopht.126.11.1539. PubMed PMID: 19001221; PubMed Central PMCID: PMCPmc2728474.
  12. Armenian SH, Panigrahy A, Murphree AL, Jubran RF. Management of retinoblastoma with proximal optic nerve enhancement on MRI at diagnosis. Pediatric blood & cancer. 2008;51(4):479-84. Epub 2008/05/15. doi: 10.1002/pbc.21604. PubMed PMID: 18478574.
  13. Tawansy KA, Samuel MA, Shammas M, Murphree AL. Vitreoretinal complications of retinoblastoma treatment. Retina (Philadelphia, Pa). 2006;26(7 Suppl):S47-52. Epub 2006/09/02. doi: 10.1097/01.iae.0000225350.83931.f6. PubMed PMID: 16946679.
  14. Pontes de Carvalho RA, Krausse ML, Murphree AL, Schmitt EE, Campochiaro PA, Maumenee IH. Delivery from episcleral exoplants. Investigative ophthalmology & visual science. 2006;47(10):4532-9. Epub 2006/09/28. doi: 10.1167/iovs.06-0030. PubMed PMID: 17003449.
  15. Khurana RN, Samuel MA, Murphree AL, Loo RH, Tawansy KA. Subfoveal nodule in Coats’ disease. Clinical & experimental ophthalmology. 2005;33(3):301-2. Epub 2005/06/04. doi: 10.1111/j.1442-9071.2005.01012.x. PubMed PMID: 15932538.
  16. Jubran RF, Erdreich-Epstein A, Butturini A, Murphree AL, Villablanca JG. Approaches to treatment for extraocular retinoblastoma: Children’s Hospital Los Angeles experience. Journal of pediatric hematology/oncology. 2004;26(1):31-4. Epub 2004/01/07. PubMed PMID: 14707710.
  17. Marback EF, Arias VE, Paranhos A, Jr., Soares FA, Murphree AL, Erwenne CM. Tumour angiogenesis as a prognostic factor for disease dissemination in retinoblastoma. The British journal of ophthalmology. 2003;87(10):1224-8. Epub 2003/09/26. PubMed PMID: 14507753; PubMed Central PMCID: PMCPmc1920792.
  18. Girvigian MR, Astrahan MA, Lim JI, Murphree AL, Tsao-Wei D, Petrovich Z. Episcleral plaque 125I radiotherapy with episcleral LCF hyperthermia: a prospective randomized trial. Brachytherapy. 2003;2(4):229-39. Epub 2004/04/06. doi: 10.1016/j.brachy.2003.08.002. PubMed PMID: 15062131.
  19. Fountain TR, Goldberger S, Murphree AL. Orbital development after enucleation in early childhood. Ophthalmic plastic and reconstructive surgery. 1999;15(1):32-6. Epub 1999/02/09. PubMed PMID: 9949427.
  20. Kolin T, Yang M, Murphree AL. Trisomy 8p and Rieger malformation. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus. 1998;2(1):61-2. Epub 1999/10/26. PubMed PMID: 10532370.
  21. Ragge NK, Acheson J, Murphree AL. Iris mammillations: significance and associations. Eye (London, England). 1996;10 ( Pt 1):86-91. Epub 1996/01/01. doi: 10.1038/eye.1996.13. PubMed PMID: 8763309.
  22. Petrovich Z, Pike M, Astrahan MA, Luxton G, Murphree AL, Liggett PE. Episcleral plaque thermoradiotherapy of posterior uveal melanomas. American journal of clinical oncology. 1996;19(2):207-11. Epub 1996/04/01. PubMed PMID: 8610652.
  23. Murphree AL, Villablanca JG, Deegan WF, 3rd, Sato JK, Malogolowkin M, Fisher A, et al. Chemotherapy plus local treatment in the management of intraocular retinoblastoma. Archives of ophthalmology (Chicago, Ill : 1960). 1996;114(11):1348-56. Epub 1996/11/01. PubMed PMID: 8906025.
  24. Kovanlikaya A, Nelson MD, Jr., Murphree AL. Radiological case of the month. Retinoblastoma presenting with orbital cellulitis. Archives of pediatrics & adolescent medicine. 1996;150(8):873-4. Epub 1996/08/01. PubMed PMID: 8704897.
  25. Fisher AM, Murphree AL, Gomer CJ. Clinical and preclinical photodynamic therapy. Lasers in surgery and medicine. 1995;17(1):2-31. Epub 1995/01/01. PubMed PMID: 7564853.
  26. Mitchell MS, Liggett PE, Green RL, Kan-Mitchell J, Murphree AL, Dean G, et al. Sustained regression of a primary choroidal melanoma under the influence of a therapeutic melanoma vaccine. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 1994;12(2):396-401. Epub 1994/02/01. PubMed PMID: 8113847.
  27. Huang XQ, Mitchell MS, Liggett PE, Murphree AL, Kan-Mitchell J. Non-fastidious, melanoma-specific CD8+ cytotoxic T lymphocytes from choroidal melanoma patients. Cancer immunology, immunotherapy : CII. 1994;38(6):399-405. Epub 1994/06/01. PubMed PMID: 8205561.
  28. Ragge NK, Falk RE, Cohen WE, Murphree AL. Images of Lisch nodules across the spectrum. Eye (London, England). 1993;7 ( Pt 1):95-101. Epub 1993/01/01. doi: 10.1038/eye.1993.20. PubMed PMID: 8325432.
  29. Fung YK, T’Ang A, Murphree AL, Zhang FH, Qiu WR, Wang SW, et al. The Rb gene suppresses the growth of normal cells. Oncogene. 1993;8(10):2659-72. Epub 1993/10/01. PubMed PMID: 8378078.
  30. Adler R, Lappe M, Murphree AL. Pupil dilation at the first well baby examination for documenting choroidal light reflex. The Journal of pediatrics. 1991;118(2):249-52. Epub 1991/02/01. PubMed PMID: 1993955.
  31. Leach RJ, Magewu AN, Buckley JD, Benedict WF, Rother C, Murphree AL, et al. Preferential retention of paternal alleles in human retinoblastoma: evidence for genomic imprinting. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. 1990;1(9):401-6. Epub 1990/09/01. PubMed PMID: 1981144.
  32. Fox BE, O’Brien CO, Kangas KJ, Murphree AL, Wright KW. Use of high dose chloral hydrate for ophthalmic exams in children: a retrospective review of 302 cases. Journal of pediatric ophthalmology and strabismus. 1990;27(5):242-4. Epub 1990/09/01. PubMed PMID: 2246736.
  33. Mihara K, Cao XR, Yen A, Chandler S, Driscoll B, Murphree AL, et al. Cell cycle-dependent regulation of phosphorylation of the human retinoblastoma gene product. Science (New York, NY). 1989;246(4935):1300-3. Epub 1989/12/08. PubMed PMID: 2588006.
  34. T’Ang A, Varley JM, Chakraborty S, Murphree AL, Fung YK. Structural rearrangement of the retinoblastoma gene in human breast carcinoma. Science (New York, NY). 1988;242(4876):263-6. Epub 1988/10/14. PubMed PMID: 3175651.
  35. Szirth BC, Matsumoto E, Wright K, Murphree AL. Attachment for the Bausch & Lomb keratometer in pediatrics. Journal of ophthalmic nursing & technology. 1988;7(1):26-9. Epub 1988/01/01. PubMed PMID: 3336052.
  36. Gomer CJ, Rucker N, Murphree AL. Transformation and mutagenic potential of porphyrin photodynamic therapy in mammalian cells. International journal of radiation biology and related studies in physics, chemistry, and medicine. 1988;53(4):651-9. Epub 1988/04/01. PubMed PMID: 2965114.
  37. Gomer CJ, Rucker N, Murphree AL. Differential cell photosensitivity following porphyrin photodynamic therapy. Cancer research. 1988;48(16):4539-42. Epub 1988/08/15. PubMed PMID: 2969280.
  38. Gomer CJ, Ferrario A, Hayashi N, Rucker N, Szirth BC, Murphree AL. Molecular, cellular, and tissue responses following photodynamic therapy. Lasers in surgery and medicine. 1988;8(5):450-63. Epub 1988/01/01. PubMed PMID: 2976443.
  39. Benedict WF, Fung YK, Murphree AL. The gene responsible for the development of retinoblastoma and osteosarcoma. Cancer. 1988;62(8 Suppl):1691-4. Epub 1988/10/15. PubMed PMID: 3167788.
  40. Szirth BC, Matsumoto E, Wright KW, Murphree AL. Attachment for the Bausch & Lomb keratometer in pediatrics. Journal of pediatric ophthalmology and strabismus. 1987;24(4):186-9. Epub 1987/07/01. PubMed PMID: 3668766.
  41. Murphree AL, Cote M, Gomer CJ. The evolution of photodynamic therapy techniques in the treatment of intraocular tumors. Photochemistry and photobiology. 1987;46(5):919-23. Epub 1987/11/01. PubMed PMID: 3441513.
  42. Gomer CJ, Hayashi N, Murphree AL. The influence of sodium pentobarbital anesthesia on in vivo photodynamic therapy. Photochemistry and photobiology. 1987;46(5):843-6. Epub 1987/11/01. PubMed PMID: 3441507.
  43. Gomer CJ, Ferrario A, Murphree AL. The effect of localized porphyrin photodynamic therapy on the induction of tumour metastasis. British journal of cancer. 1987;56(1):27-32. Epub 1987/07/01. PubMed PMID: 2956984; PubMed Central PMCID: PMCPmc2001674.
  44. Fung YK, Murphree AL, T’Ang A, Qian J, Hinrichs SH, Benedict WF. Structural evidence for the authenticity of the human retinoblastoma gene. Science (New York, NY). 1987;236(4809):1657-61. Epub 1987/06/26. PubMed PMID: 2885916.
  45. Benedict WF, Srivatsan ES, Mark C, Banerjee A, Sparkes RS, Murphree AL. Complete or partial homozygosity of chromosome 13 in primary retinoblastoma. Cancer research. 1987;47(15):4189-91. Epub 1987/08/01. PubMed PMID: 2886215.
  46. Ormerod LD, Murphree AL, Gomez DS, Schanzlin DJ, Smith RE. Microbial keratitis in children. Ophthalmology. 1986;93(4):449-55. Epub 1986/04/01. PubMed PMID: 3703517.
  47. Murphree AL. Ophthalmology: recessive human cancer genes. The Western journal of medicine. 1986;144(4):455. Epub 1986/04/01. PubMed PMID: 18749965; PubMed Central PMCID: PMCPmc1306664.
  48. Gomer CJ, Rucker N, Ferrario A, Murphree AL. Expression of potentially lethal damage in Chinese hamster cells exposed to hematoporphyrin derivative photodynamic therapy. Cancer research. 1986;46(7):3348-52. Epub 1986/07/01. PubMed PMID: 3011247.
  49. Cavenee WK, Murphree AL, Shull MM, Benedict WF, Sparkes RS, Kock E, et al. Prediction of familial predisposition to retinoblastoma. The New England journal of medicine. 1986;314(19):1201-7. Epub 1986/05/08. doi: 10.1056/nejm198605083141901. PubMed PMID: 3702916.
  50. Lee WH, Murphree AL, Benedict WF. Comparison studies of oncogenes in retinoblastoma and neuroblastoma. Progress in clinical and biological research. 1985;175:131-9. Epub 1985/01/01. PubMed PMID: 3991728.
  51. Gomer CJ, Rucker N, Razum NJ, Murphree AL. In vitro and in vivo light dose rate effects related to hematoporphyrin derivative photodynamic therapy. Cancer research. 1985;45(5):1973-7. Epub 1985/05/01. PubMed PMID: 3986754.
  52. Gomer CJ, Rucker N, Murphree AL. Examination of potentially lethal damage in cells treated with hematoporphyrin derivative and red light. Advances in experimental medicine and biology. 1985;193:147-53. Epub 1985/01/01. PubMed PMID: 2937260.
  53. Gomer CJ, Jester JV, Razum NJ, Szirth BC, Murphree AL. Photodynamic therapy of intraocular tumors: examination of hematoporphyrin derivative distribution and long-term damage in rabbit ocular tissue. Cancer research. 1985;45(8):3718-25. Epub 1985/08/01. PubMed PMID: 4016749.
  54. Costin G, Murphree AL. Hypothalamic-pituitary function in children with optic nerve hypoplasia. American journal of diseases of children (1960). 1985;139(3):249-54. Epub 1985/03/01. PubMed PMID: 2983530.
  55. Chan CC, Benezra D, Rodrigues MM, Palestine AG, Hsu SM, Murphree AL, et al. Immunohistochemistry and electron microscopy of choroidal infiltrates and Dalen-Fuchs nodules in sympathetic ophthalmia. Ophthalmology. 1985;92(4):580-90. Epub 1985/04/01. PubMed PMID: 3873634.
  56. Murphree AL, Benedict WF. Retinoblastoma: clues to human oncogenesis. Science (New York, NY). 1984;223(4640):1028-33. Epub 1984/03/09. PubMed PMID: 6320372.
  57. Murphree AL. Ophthalmologic signs in genetic disease. Hospital practice (Office ed). 1984;19(12):85-92. Epub 1984/12/01. PubMed PMID: 6438138.
  58. Lee WH, Murphree AL, Benedict WF. Expression and amplification of the N-myc gene in primary retinoblastoma. Nature. 1984;309(5967):458-60. Epub 1984/05/06. PubMed PMID: 6728001.
  59. Sparkes RS, Murphree AL, Lingua RW, Sparkes MC, Field LL, Funderburk SJ, et al. Gene for hereditary retinoblastoma assigned to human chromosome 13 by linkage to esterase D. Science (New York, NY). 1983;219(4587):971-3. Epub 1983/02/25. PubMed PMID: 6823558.
  60. Gomer CJ, Doiron DR, Jester JV, Szirth BC, Murphree AL. Hematoporphyrin derivative photoradiation therapy for the treatment of intraocular tumors: examination of acute normal ocular tissue toxicity. Cancer research. 1983;43(2):721-7. Epub 1983/02/01. PubMed PMID: 6216946.
  61. Bowns GT, Walls RP, Murphree AL, Ortega J. Neonatal neuroblastoma metastatic to the iris. Cancer. 1983;52(5):929-31. Epub 1983/09/01. PubMed PMID: 6871833.
  62. Benedict WF, Murphree AL, Banerjee A, Spina CA, Sparkes MC, Sparkes RS. Patient with 13 chromosome deletion: evidence that the retinoblastoma gene is a recessive cancer gene. Science (New York, NY). 1983;219(4587):973-5. Epub 1983/02/25. PubMed PMID: 6336308.
  63. Benedict WF, Banerjee A, Mark C, Murphree AL. Nonrandom chromosomal changes in untreated retinoblastomas. Cancer genetics and cytogenetics. 1983;10(4):311-33. Epub 1983/12/01. PubMed PMID: 6652613.
  64. Murphree AL, Gomer CJ, Doiron DR, Benedict WF. Recent developments in the genetics and treatment of retinoblastoma. Birth defects original article series. 1982;18(6):681-7. Epub 1982/01/01. PubMed PMID: 7171784.
  65. Gomer CJ, Rucker N, Mark C, Benedict WF, Murphree AL. Tissue distribution of 3H-hematoporphyrin derivative in athymic “nude” mice heterotransplanted with human retinoblastoma. Investigative ophthalmology & visual science. 1982;22(1):118-20. Epub 1982/01/01. PubMed PMID: 7056618.
  66. Diddie KR, Dinsmore S, Murphree AL. Total hyphema evacuation by vitrectomy instrumentation. Ophthalmology. 1981;88(9):917-21. Epub 1981/09/01. PubMed PMID: 7301308.
  67. Sparkes RS, Sparkes MC, Wilson MG, Towner JW, Benedict W, Murphree AL, et al. Regional assignment of genes for human esterase D and retinoblastoma to chromosome band 13q14. Science (New York, NY). 1980;208(4447):1042-4. Epub 1980/05/30. PubMed PMID: 7375916.
  68. Benedict WF, Lingua RW, Doiron DR, Dawson JA, Murphree AL. Tumor regression of human retinoblastoma in the nude mouse following photoradiation therapy: a preliminary report. Medical and pediatric oncology. 1980;8(4):397-401. Epub 1980/01/01. PubMed PMID: 7453671.
  69. Benedict WF, Dawson JA, Banerjee A, Murphree AL. The nude mouse model for human retinoblastoma: a system for evaluation of retinoblastoma therapy. Medical and pediatric oncology. 1980;8(4):391-5. Epub 1980/01/01. PubMed PMID: 6935497.
  70. Murphree AL, Beaudet AL, Palmer EA, Nichols BL, Jr. Cataract in mannosidosis. Birth defects original article series. 1976;12(3):319-34. Epub 1976/01/01. PubMed PMID: 953197.
  71. Arbisser AI, Murphree AL, Garcia CA, Howell RR. Ocular findings in mannosidosis. American journal of ophthalmology. 1976;82(3):465-71. Epub 1976/09/01. PubMed PMID: 961797.
  72. Hittner HM, Murphree AL, Garcia CA, Justice J, Jr., Chokshi DB. Dominant cone-rod dystrophy. Documenta ophthalmologica Advances in ophthalmology. 1975;39(1):29-52. Epub 1975/12/01. PubMed PMID: 1201699.