DoctorsJonathan W. Kim, MD

Jonathan W. Kim, MD

Title: Associate Professor of Clinical Ophthalmology, A. Linn Murphree Professor, Director of the Ocular Oncology Service, USC Department of Ophthalmology, The Vision Center at Childrens Hospital Of Los Angeles

Department: Ophthalmology

Clinical Specialty: Neuro-Ophthalmology, Pediatric Ophthalmology, and Ocular Oncology

Treatment Expertise: Neuro-Ophthalmology, Pediatric and Adult Ocular Oncology, Melanoma, Retinoblastoma, Ocular Plastics

Certification: American Board of Ophthalmology

Language: English, Korean

Location: Los Angeles and Children's Hospital Los Angeles

Biography and Education

Biography

Jonathan W. Kim, MD, earned his medical degree at the University of Iowa in 1994 and completed his residency in ophthalmology at the California Pacific Medical Center in 1998. A rare accomplishment, Dr. Kim is fellowship trained in three subspecialties, neuro-ophthalmology, oculoplastic surgery and ocular oncology. Jonathan Kim, MD, also serves as the A. Linn Murphree Retinoblastoma Program Chair and director of The Vision Center at the Children’s Hospital Los Angeles (CHLA), leading the Ocular Oncology service and Retinoblastoma Service. Dr. Kim has won several teaching and mentorship awards and is actively involved in resident teaching at the USC Roski Eye Institute. He is dedicated to advancing research in the development of targeted therapies for retinoblastomas in the field of ocular oncology. Dr. Kim was also recognized as a top doctor in Pasadena Magazine 2013 and 2014.

Research Interests:

Dr. Kim is currently involved in several research projects, including a Phase I study to evaluate the clinical feasibility of treating retinoblastoma with a novel episcleral implant which delivers sustained levels of chemotherapy through a trans-scleral delivery method. He is also a co-investigator on translational research projects in the areas of photodynamic therapy and anti-survivin inhibitor molecules.

Education

  • MD, University of Iowa 1994

Internship

  • Mercy Hospital, Transitional Medicine, 1994-1995

Residency

  • California Pacific Medical Center, Ophthalmology, 1995-1998

Fellowship

  • Massachusetts Eye & Ear Infirmary, Harvard Medical, Neuro-ophthalmology, 2003-2004
  • UCLA/Jules Stein Eye Institute, Oculoplastic Surgery, 1999-2000
  • Royal Liverpool University Hospital, Ocular Oncology, 1999

Accomplishments

Professional society memberships

  • American Academy of Ophthalmology American Society of Ophthalmic Plastic and Reconstructive Surgery (ASOPRS) North
  • American Neuro-Ophthalmology Society of Heeds Fellows, Cleveland, Ohio
  • Alpha Omega Alpha, Medical Honor Society
  • Children’s Oncology Group Los Angeles Society of Ophthalmology

Awards

  • National Award for Outstanding Thesis, American Society of Ophthalmic Plastic and Erdbrink Resident Research Award, California Pacific Medical Center (CPMC) Department of Ophthalmology, 1997
  • Heed Fellow, Heed Ophthalmic Foundation, 1999-2000
  • Sanford and Erna Schulhofer Fellow, Jules Stein Eye Institute, UCLA, 1999-2000
  • Reconstructive Surgery (ASOPRS), Annual meeting, New Orleans, Louisiana, 2001
  • Resident Teacher Award, Department of Ophthalmology, University of California, Irvine, 2006
  • Achievement Award, American Academy of Ophthalmology (AAO), 2007
  • Resident Teacher Award, Department of Ophthalmology, Stanford Medical Center, 2008
  • Mentorship award, Stanford Biodesign Fellows Program, 2011
  • Knowledge Base Panel for Ocular Oncology, American Academy of Ophthalmology, 2013
  • Pasadena Magazine Top Doctors in Ophthalmology, 2013
  • Pasadena Magazine Top Doctors in Ophthalmology, 2014
  • Oculoplastics Reviewer, Annual Meeting Program Subcommittee, American Academy of Ophthalmology, 2016
  • Subcommittee Knowledge Base Member, Ophthalmic Pathology and Oncology Panel, American Academy of Ophthalmology, 2016

Publications

  1. Lee NS, Evgrafov OV, Souaiaia T, Bonyad A, Herstein J, Lee JY, et al. Non-coding RNAs derived from an alternatively spliced REST transcript (REST-003) regulate breast cancer invasiveness. Scientific reports. 2015;5.
  2. Kim JW. Retinoblastoma: evidence for postenucleation adjuvant chemotherapy. International ophthalmology clinics. 2015;55(1):77-96. Epub 2014/12/02. doi: 10.1097/iio.0000000000000048. PubMed PMID: 25436495.
  3. Browne AW, Dandapani SV, Jennelle R, Stevanovic M, Lee TC, Murphree AL, et al. Outcomes of medium choroidal melanomas treated with ruthenium brachytherapy guided by three-dimensional pretreatment modeling. Brachytherapy. 2015;14(5):718-25. Epub 2015/06/16. doi: 10.1016/j.brachy.2015.04.010. PubMed PMID: 26073224.
  4. Berry JL, Jubran R, Lee TC, Murphree AL, Lee D, Kim JW. Low-Dose Chemoreduction for Infants Diagnosed with Retinoblastoma before 6 Months of Age. Ocular Oncology and Pathology. 2015;1(2):103-10.
  5. Nugent AK, Paulus YM, Chan A, Kim JW, Schwartz EJ, Moshfeghi DM. Multiple myeloma recurrence with optic nerve infiltration diagnosed by vitrectomy, immunohistochemistry, and in situ hybridization. European journal of ophthalmology. 2014;24(3):446-8. Epub 2013/11/19. doi: 10.5301/ejo.5000392. PubMed PMID: 24242215.
  6. Kim JW, Ngai LK, Sadda S, Murakami Y, Lee DK, Murphree AL. Retcam fluorescein angiography findings in eyes with advanced retinoblastoma. The British journal of ophthalmology. 2014;98(12):1666-71. Epub 2014/07/24. doi: 10.1136/bjophthalmol-2014-305180. PubMed PMID: 25053763.
  7. Choudhri O, Feroze AH, Lad EM, Kim JW, Plowey ED, Karamchandani JR, et al. Co-occurrence of a cerebral cavernous malformation and an orbital cavernous hemangioma in a patient with seizures and visual symptoms: Rare crossroads for vascular malformations. Surgical neurology international. 2014;5(Suppl 4):S148-54. Epub 2014/07/30. doi: 10.4103/2152-7806.134810. PubMed PMID: 25071938; PubMed Central PMCID: PMCPmc4109172.
  8. Berry JL, Jubran R, Wong K, Lee TC, Murphree AL, Kim JW. Factors predictive of long-term visual outcomes of Group D eyes treated with chemoreduction and low-dose IMRT salvage: the Children’s Hospital Los Angeles experience. The British journal of ophthalmology. 2014;98(8):1061-5. Epub 2014/03/29. doi: 10.1136/bjophthalmol-2013-304411. PubMed PMID: 24671926.
  9. Riess JW, Nagpal S, Das M, Neal JW, Kim JW, Wakelee HA. A case series of NSCLC patients with different molecular characteristics and choroidal metastases: improvement in vision with treatment including pemetrexed and bevacizumab. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2013;8(2):e17-8. Epub 2013/01/19. doi: 10.1097/JTO.0b013e31827690da. PubMed PMID: 23328555; PubMed Central PMCID: PMCPmc3552378.
  10. Ko MJ, Morris CK, Kim JW, Lad SP, Arrigo RT, Lad EM. Orbital fractures: national inpatient trends and complications. Ophthalmic plastic and reconstructive surgery. 2013;29(4):298-303. Epub 2013/06/20. doi: 10.1097/IOP.0b013e318295f91d. PubMed PMID: 23778290.
  11. Berry JL, Jubran R, Kim JW, Wong K, Bababeygy SR, Almarzouki H, et al. Long-term outcomes of Group D eyes in bilateral retinoblastoma patients treated with chemoreduction and low-dose IMRT salvage. Pediatric blood & cancer. 2013;60(4):688-93. Epub 2012/09/22. doi: 10.1002/pbc.24303. PubMed PMID: 22997170.
  12. Berry JL, Dandapani SV, Stevanovic M, Lee TC, Astrahan M, Murphree AL, et al. Outcomes of choroidal melanomas treated with eye physics: a 20-year review. JAMA ophthalmology. 2013;131(11):1435-42. Epub 2013/09/07. doi: 10.1001/jamaophthalmol.2013.4422. PubMed PMID: 24008431.
  13. Kim J, Do H, Egbert P. Enucleated eyes after failed intra-arterial infusion of chemotherapy for unilateral retinoblastoma: histopathologic evaluation of vitreous seeding. Clinical ophthalmology (Auckland, NZ). 2011;5:1655.
  14. Kim JW, Yau JW, Moshfeghi D, Fishman M. Orbital fibrosis and intraocular recurrence of retinoblastoma following periocular carboplatin. Journal of pediatric ophthalmology and strabismus. 2010;47 Online:e1-4. Epub 2011/01/11. doi: 10.3928/01913913-20100510-03. PubMed PMID: 21214147.
  15. Kim JW, Lee DK, Fishman M. Orbital smooth muscle tumor associated with epstein-barr virus in a human immunodeficiency virus-positive patient. Archives of ophthalmology (Chicago, Ill : 1960). 2010;128(8):1084-5. Epub 2010/08/11. doi: 10.1001/archophthalmol.2010.146. PubMed PMID: 20697018.
  16. Novetsky DE, Abramson DH, Kim JW, Dunkel IJ. Published international classification of retinoblastoma (ICRB) definitions contain inconsistencies–an analysis of impact. Ophthalmic genetics. 2009;30(1):40-4. Epub 2009/01/28. doi: 10.1080/13816810802452168. PubMed PMID: 19172510.
  17. Kim JW, Yates BS, Goldberg RA. Total lateral orbitotomy. Orbit (Amsterdam, Netherlands). 2009;28(6):320-7. Epub 2009/11/26. doi: 10.3109/01676830903334028. PubMed PMID: 19929652.
  18. Kim JW, Lee DK. Unusual eyelid, periocular, and periorbital cutaneous malignancies. International ophthalmology clinics. 2009;49(4):77-96. Epub 2010/03/30. doi: 10.1097/IIO.0b013e3181b7f3f7. PubMed PMID: 20348859.
  19. Kim JW, Kathpalia V, Dunkel IJ, Wong RK, Riedel E, Abramson DH. Orbital recurrence of retinoblastoma following enucleation. British Journal of Ophthalmology. 2009;93(4):463-7.
  20. Kamdar NV, Erko A, Ehrlich JS, Kim JW, Kambham N, Chertow GM. Choroidopathy and kidney disease: a case report and review of the literature. Cases journal. 2009;2:7425. Epub 2009/10/16. doi: 10.1186/1757-1626-2-7425. PubMed PMID: 19829960; PubMed Central PMCID: PMCPmc2740249.
  21. Brodie SE, Pierre Gobin Y, Dunkel IJ, Kim JW, Abramson DH. Persistence of retinal function after selective ophthalmic artery chemotherapy infusion for retinoblastoma. Documenta ophthalmologica Advances in ophthalmology. 2009;119(1):13-22. Epub 2009/01/27. doi: 10.1007/s10633-008-9164-3. PubMed PMID: 19169884.
  22. Szabo KA, Cheshier SH, Kalani MY, Kim JW, Guzman R. Supraorbital approach for repair of open anterior skull base fracture. Journal of neurosurgery Pediatrics. 2008;2(6):420-3. Epub 2008/11/28. doi: 10.3171/ped.2008.2.12.420. PubMed PMID: 19035689.
  23. Martin NE, Kim JW, Abramson DH. Fibrin sealant for retinoblastoma: where are we? Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. 2008;24(5):433-8. Epub 2008/09/16. doi: 10.1089/jop.2007.0110. PubMed PMID: 18788992.
  24. Kim JW, Abramson DH. Topical treatment options for conjunctival neoplasms. Clinical ophthalmology (Auckland, NZ). 2008;2(3):503-15. Epub 2009/08/12. PubMed PMID: 19668748; PubMed Central PMCID: PMCPmc2694026.
  25. Abramson DH, Dunkel IJ, Brodie SE, Kim JW, Gobin YP. A phase I/II study of direct intraarterial (ophthalmic artery) chemotherapy with melphalan for intraocular retinoblastoma initial results. Ophthalmology. 2008;115(8):1398-404, 404.e1. Epub 2008/03/18. doi: 10.1016/j.ophtha.2007.12.014. PubMed PMID: 18342944.
  26. Reiser BJ, Mok A, Kukes G, Kim JW. Non-AIDS-related Kaposi sarcoma involving the tarsal conjunctiva and eyelid margin. Archives of ophthalmology (Chicago, Ill : 1960). 2007;125(6):838-40. Epub 2007/06/15. doi: 10.1001/archopht.125.6.838. PubMed PMID: 17563000.
  27. Lessell S, Kim JW, Hatton MP, Stemmer-Rachamimov A, Thiagalingham S, Rubin PA. Clinical without histopathological manifestations of inflammation in a patient with primary intraorbital optic nerve sheath meningioma. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society. 2007;27(2):104-6. Epub 2007/06/06. doi: 10.1097/WNO.0b013e318064e495. PubMed PMID: 17548993.
  28. Kim JW, Abramson DH, Dunkel IJ. Current management strategies for intraocular retinoblastoma. Drugs. 2007;67(15):2173-85. Epub 2007/10/12. PubMed PMID: 17927283.
  29. Kim JW, Hills WL, Rizzo JF, Egan RA, Lessell S. Ischemic optic neuropathy following spine surgery in a 16-year-old patient and a ten-year-old patient. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society. 2006;26(1):30-3. Epub 2006/03/07. doi: 10.1097/01.wno.0000205980.32023.2d. PubMed PMID: 16518163.
  30. Kim JW, Rizzo JF, Lessell S. Delayed visual decline in patients with “stable” optic neuropathy. Archives of ophthalmology (Chicago, Ill : 1960). 2005;123(6):785-8. Epub 2005/06/16. doi: 10.1001/archopht.123.6.785. PubMed PMID: 15955979.
  31. Kim JW, Rizzo JF, Lessell S. Controversies in the management of optic nerve sheath meningiomas. International ophthalmology clinics. 2005;45(4):15-23. Epub 2005/10/04. PubMed PMID: 16199964.
  32. Goldberg RA, Kim JW, Shorr N. Orbital exenteration: results of an individualized approach. Ophthalmic plastic and reconstructive surgery. 2003;19(3):229-36. Epub 2003/08/16. PubMed PMID: 12918560.
  33. Kim JW, Goldberg RA, Shorr N. The inferomedial orbital strut: an anatomic and radiographic study. Ophthalmic plastic and reconstructive surgery. 2002;18(5):355-64. Epub 2002/09/28. doi: 10.1097/01.iop.0000024421.95472.41. PubMed PMID: 12352822.
  34. Kim JW, Damato BE, Hiscott P. Noncontiguous tumor recurrence of posterior uveal melanoma after transscleral local resection. Archives of ophthalmology (Chicago, Ill : 1960). 2002;120(12):1659-64. Epub 2002/12/10. PubMed PMID: 12470139.
  35. Goldberg RA, Beizai P, Kim J, McCann JD. Use of vinyl polysiloxane impression material to protect and identify the nasolacrimal sac in endonasal dacryocystorhinostomy. Ophthalmic Plastic & Reconstructive Surgery. 2002;18(3):205-10.
  36. Kim JW, Kikkawa DO, Aboy A, Glasgow BJ. Chronic exposure of hydroxyapatite orbital implants: cilia implantation and epithelial downgrowth. Ophthalmic Plastic & Reconstructive Surgery. 2000;16(3):216-22.
  37. Kim JW, Stewart WB, Spencer WH, Ellis DS. Acute expansion of an orbital vascular malformation. Archives of ophthalmology. 1999;117(6):844-5.
  38. Kim JW, Ellis DS, Stewart WB. Correction of lower eyelid retraction by transconjunctival retractor excision and lateral eyelid suspension. Ophthalmic plastic and reconstructive surgery. 1999;15(5):341-8. Epub 1999/10/08. PubMed PMID: 10511214.
  39. Toth BA, Kim JW, Chin M, Cedars M. Distraction osteogenesis and its application to the midface and bony orbit in craniosynostosis syndromes. The Journal of craniofacial surgery. 1998;9(2):100-13; discussion 19-22. Epub 1998/05/20. PubMed PMID: 9586536.
  40. Kim JW, McDonald HR, Rubsamen PE, Luttrull JK, Drouilhet JH, Frambach DA, et al. Surfing-related ocular injuries. Retina (Philadelphia, Pa). 1998;18(5):424-9. Epub 1998/11/04. PubMed PMID: 9801037.
  41. Kim JW, Kikkawa DO, Lemke BN. Donor site complications of hard palate mucosal grafting. Ophthalmic plastic and reconstructive surgery. 1997;13(1):36-9. Epub 1997/03/01. PubMed PMID: 9076782.
  42. Kikkawa DO, Kim JW. Asian blepharoplasty. International ophthalmology clinics. 1997;37(3):193-204. Epub 1997/07/01. PubMed PMID: 9279651.
  43. Kikkawa DO, Kim JW. Lower-eyelid blepharoplasty. International ophthalmology clinics. 1997;37(3):163-78. Epub 1997/07/01. PubMed PMID: 9279649.