< BackResearch FacultyFarhad Hafezi, MD, PhD

Farhad Hafezi, MD, PhD


Professor of Ophthalmology – University of Geneva, Switzerland and Clinical Professor of Ophthalmology – Keck School of Medicine, USC

Research Topics:

Corneal infection
Ocular biomechanics
Crosslinking, CXL
Cell biology

Clinical Interests:

Cornea and External Diseases

Research Interests:

Farhad Hafezi’s main research interests are corneal wound healing, corneal infection, ocular biomechanics, and progressive myopia. The common link among these interests is a treatment modality that is now used in clinical ophthalmology for corneal diseases and dystrophies. This modality is called corneal cross-linking (CXL). CXL combines UV light and riboflavin (Vitamin B2) to modify collagen structure and biomechanics. The newest clinical application is using CXL to treat bacterial and fungal corneal infections (PACK-CXL).


Farhad Hafezi (1967) studied medicine at the University of Fribourg and University of Bern in Switzerland. He is married, has three daughters and resides in Zug, Switzerland.

Prof. Hafezi’s clinical focus is the cornea and complication management after complicated refractive laser surgery. He was instrumental in implementing corneal cross-linking technology in ophthalmology, which is currently performed in over 125 countries.

From 2010 to 2014, Farhad Hafezi was the Chairman of the Department of Ophthalmology of the Geneva University Hospitals, Geneva, Switzerland, and Full Professor of Ophthalmology at the University of Geneva. In 2012, he was also appointed Clinical Professor of Ophthalmology at the Department of Ophthalmology, Keck School of Medicine, University of Southern California (USC) Los Angeles. While Prof. Hafezi remains a professor at the University of Geneva, in 2014, he founded the ELZA Institute AG in Zurich, Switzerland where he serves as the chief medical officer. All his clinical activities are conducted at the ELZA Institute.

In 2015, Prof. Hafezi transferred his research group focused on ocular cell biology at the CABMM from the University of Geneva to the University of Zurich. At the same time, Prof. Hafezi and his wife founded the Light for Sight Foundation (Zurich, Switzerland), which is an international initiative dedicated to eliminating preventable blindness among children and adolescents with keratoconus.

Prof. Hafezi has published more than 160 scientific articles. His work has been cited more than 5’000 times with a total impact factor of 448 and an h index of 36.

He is an Associate Editor of the "Journal of Refractive Surgery" and on the Editorial Board of the "International Journal of Keratoconus and Ectatic Corneal Disease”, “Current Eye Research” and the "Iranian Journal of Ophthalmology”. He frequently moderates courses at the ESCRS (European Society for Cataract and Refractive Surgery) and the AAO (American Academy of Ophthalmology). Prof. Hafezi is a member of the Advisory Board of “Global ONE”, the educational network of the American Academy of Ophthalmology (AAO).


    • Internship: University of Zurich, Switzerland
    • Residency: University of Zurich, Switzerland
    • Fellowship: Rotterdam Eye Hospital, The Netherlands


  • Poster Prize of the Swiss Ophthalmological Society, 1995
  • Poster Prize of the Swiss Ophthalmological Society, 1996
  • Alfred Vogt Prize of the Swiss Ophthalmological Society, 1997
  • Cover Article in “Nature Medicine,” 1997
  • Jules Francois Prize of the Belgian Ophthalmological Society, Highest Belgian Award for Ophthalmology, 2000
  • Retinitis Pigmentosa Research Award from Retina Suisse and ProRetina Germany, 2000
  • Poster Prize of the Swiss Ophthalmological Society, 2001
  • Georg Friedrich Götz Prize, Highest Medical Award of the University of Zurich, 2002
  • Swiss Economic Award 2007, Finalist, 2007
  • Keratoconus Award of the Global Keratoconus Foundation, 2009
  • Isaac Bekhor lecture, Doheny Eye Institute, University of Southern California Los Angeles, USA, 2011
  • David Easty Lecture, XIVth Bowman Club Meeting, Newcastle Upon Tyne, GB, 2011
  • Innovation Award of the Geneva University Hospitals, 2012
  • VentureKick Stage 1 for Promoting Business Ideas at Swiss Universities, 2012
  • INNOGAP Award, University of Geneva, Most Promising Patent, 2012
  • Kok van Alphen Lecture, Meeting of the Dutch Ophthalmological Society, 2013
  • Carl Camras Translational Research Award by the ARVO Foundation, USA, 2014
  • Amber Cornea, Polish Ophthalmological Society, 2014
  • Gold Medal, Intraocular Implant and Refractive Society of India (IIRSI), 2014
  • Casebeer Award, International Society of Refractive Surgery, American Academy of Ophthalmology, 2014
  • PowerList 100, The Most Influential Personalities in Ophthalmology, “The Ophthalmologist,” London, 2014
  • 40th Anniversary of the USC Eye Institute Los Angeles, Distinguished Speaker, 2015
  • Honorary Member of SHIOL, Hungary’s Society for Cataract and Refractive Surgery, 2016
  • Gold Medal, SAMIR (Société Marocaine de Chirurgie Réfractive et d’Implantologie), Casablanca, Morocco, 2016
  • El Maghrabi International Award, MEACO (Middle Eastern African Council of Ophthalmology), Bahrein, 2016
  • PowerList 100, The Most Influential Personalities in Ophthalmology, “The Ophthalmologist,” London, 2016

Other web profiles:


  1. da Cruz L, Dorn JD, Humayun MS, Dagnelie G, Handa J, Barale PO, Sahel JA, Stanga PE, Hafezi F, Safran AB, Salzmann J, Santos A, Birch D, Spencer R, Cideciyan AV, de Juan E, Duncan JL, Eliott D, Fawzi A, Olmos de Koo LC, Ho AC, Brown G, Haller J, Regillo C, Del Priore LV, Arditi A, Greenberg RJ. Five-Year Safety and Performance Results from the Argus Ii Retinal Prosthesis System Clinical Trial. Ophthalmology. 2016 Oct;123(10):2248-54.
  2. Randleman JB, Khandelwal SS, Hafezi F. Corneal Cross-Linking. Surv Ophthalmol. 2015 Nov-Dec;60(6):509-23.
  3. Ho AC, Humayun MS, Dorn J, daCruz L, Dagnelle G, Handa J, Baralle P-O, Sahel J-A, Stanga PE, Hafezi F, Safran AB, Salzmann J, Santos A, Birch D, Spencer R, Cideciyan AV, de Juan E, Duncan JL, Eliott D, Fawzi A, Olmos de Koo LC, Brown G, Haller J, Regilio C, Dep Priore L, Arditi A, Geruschat DR, Greenberg RJ, Group AIS. Long-term results from an epiretinal prosthesis to restore sight to the blind. Ophthalmology. (in press).
  4. Hammer A, Rudaz S, Guinchard S, Kling S, Richoz O, Hafezi F. Analysis of riboflavin compounds in the rabbit cornea in vivo. Current Eye Research.
  5. Gatzioufas Z, Raiskup F, O'Brart D, Spoerl E, Panos GD, Hafezi F. Transepithelial Corneal Cross-linking Using an Enhanced Riboflavin Solution. Journal of Refractive Surgery.
  6. Tabibian D, Mazzotta C, Hafezi F. PACK-CXL: Corneal cross-linking in infectious keratitis. Eye Vis (Lond). 2016. 3: 11. 10.1186/s40662-016-0042-x.
  7. Peyman A, Nouralishahi A, Hafezi F, Kling S, Peyman M. Stromal Demarcation Line in Pulsed Versus Continuous Light Accelerated Corneal Cross-linking for Keratoconus. J Refract Surg. 2016. 32(3): 206-08. 10.3928/1081597X-20160204-03.
  8. Tabibian D, Richoz O, Hafezi F. PACK-CXL: Corneal Cross-linking for Treatment of Infectious Keratitis. J Ophthalmic Vis Res. 2015. 10(1): 77-80. 10.4103/2008-322X.156122. 4424723.
  9. Stanescu-Segall D, Birke K, Wenzel A, Grimm C, Orgul S, Fischer JA, Born W, Hafezi F. PAX6 Expression and Retinal Cell Death in a Transgenic Mouse Model for Acute Angle-Closure Glaucoma. J Glaucoma. 2015. 10.1097/IJG.0b013e318207069b.
  10. Randleman JB, Khandelwal SS, Hafezi F. Corneal Cross-Linking. Surv Ophthalmol. 2015. 10.1016/j.survophthal.2015.04.002.
  11. Pot SA, Gallhofer NS, Walser-Reinhardt L, Hafezi F, Spiess BM. Treatment of bullous keratopathy with corneal collagen cross-linking in two dogs. Vet Ophthalmol. 2015. 18(2): 168-73. 10.1111/vop.12137.
  12. Panos GD, Song X, Hafezi F, Seitz B, Langenbucher A, Gatzioufas Z. Corneal biomechanical properties in patients with Graves' Disease. Acta Ophthalmol. 2015. 93(4): e320-1. 10.1111/aos.12563.
  13. Mazzotta C, Hafezi F, Kymionis G, Caragiuli S, Jacob S, Traversi C, Barabino S, Randleman B. In Vivo Confocal Microscopy after Corneal Collagen Cross-Linking. Ocul Surf. 2015. 10.1016/j.jtos.2015.04.007.
  14. Mansouri K, Pajic B, Hafezi F. Effect of cigarette smoking on intraocular pressure. J Cataract Refract Surg. 2015. 41(3): 682-3. 10.1016/j.jcrs.2014.11.040.
  15. Kling S, Richoz O, Hammer A, Tabibian D, Jacob S, Agarwal A, Hafezi F. Increased Biomechanical Efficacy of Corneal Cross-linking in Thin Corneas Due to Higher Oxygen Availability. J Refract Surg. 2015. 31(12): 840-6. 10.3928/1081597X-20151111-08.
  16. Hashemi H, Miraftab M, Seyedian MA, Hafezi F, Bahrmandy H, Heidarian S, Amanzadeh K, Nikbin H, Fotouhi A, Asgari S. Long-term results of an accelerated corneal cross-linking protocol 18mW/cm for the treatment of progressive keratoconus. Am J Ophthalmol. 2015. 10.1016/j.ajo.2015.08.027.
  17. Hashemi H, Miraftab M, Hafezi F, Asgari S. Matched Comparison Study of Total and Partial Epithelium Removal in Corneal Cross-linking. J Refract Surg. 2015. 31(2): 110-5. 10.3928/1081597X-20150122-06.
  18. Hammer A, Kling S, Boldi MO, Richoz O, Tabibian D, Randleman JB, Hafezi F. Establishing Corneal Cross-Linking With Riboflavin and UV-A in the Mouse Cornea In Vivo: Biomechanical Analysis. Invest Ophthalmol Vis Sci. 2015. 56(11): 6581-90. 10.1167/iovs.15-17426.
  19. Gomes JA, Tan D, Rapuano CJ, Belin MW, Ambrosio R, Jr., Guell JL, Malecaze F, Nishida K, Sangwan VS, Group of Panelists for the Global Delphi Panel of K, Ectatic D. Global consensus on keratoconus and ectatic diseases. Cornea. 2015. 34(4): 359-69. 10.1097/ICO.0000000000000408.
  20. Gatzioufas Z, Panos GD, Tabibian D, Hafezi F. Ocular anterior segment changes and corneal biomechanics in pregnancy. J Cataract Refract Surg. 2015. 41(2): 480-1. 10.1016/j.jcrs.2014.12.041.
  21. Bortolotto T, Bahillo J, Richoz O, Hafezi F, Krejci I. Failure analysis of adhesive restorations with SEM and OCT: from marginal gaps to restoration loss. Clin Oral Investig. 2015. 10.1007/s00784-015-1402-y.
  22. Tabibian D, Richoz O, Riat A, Schrenzel J, Hafezi F. Accelerated Photoactivated Chromophore for Keratitis-Corneal Collagen Cross-linking as a First-line and Sole Treatment in Early Fungal Keratitis. J Refract Surg. 2014. 30(12): 855-57. 10.3928/1081597X-20141113-06.
  23. Said DG, Gatzioufas Z, Hafezi F. Author reply: Collagen Cross-Linking with Photoactivated Riboflavin (PACK-CXL) for the Treatment of Advanced Infectious Keratitis with Corneal Melting. Ophthalmology. 2014. 10.1016/j.ophtha.2014.06.044.
  24. Said DG, Elalfy MS, Gatzioufas Z, El-Zakzouk ES, Hassan MA, Saif MY, Zaki AA, Dua HS, Hafezi F. Collagen Cross-Linking with Photoactivated Riboflavin (PACK-CXL) for the Treatment of Advanced Infectious Keratitis with Corneal Melting. Ophthalmology. 2014. 121(7): 1377-82. 10.1016/j.ophtha.2014.01.011.
  25. Richoz O, Tabibian D, Hammer A, Majo F, Nicolas M, Hafezi F. The Effect of Standard and High-Fluence Corneal Cross-Linking (CXL) on Cornea and Limbus. Invest Ophthalmol Vis Sci. 2014. 55(9): 5783-7. 10.1167/iovs.14-14695.
  26. Richoz O, Kling S, Zandi S, Hammer A, Spoerl E, Hafezi F. A constant-force technique to measure corneal biomechanical changes after collagen cross-linking. PLoS One. 2014. 9(8): e105095. 10.1371/journal.pone.0105095. 4146533.
  27. Richoz O, Kling S, Hoogewoud F, Hammer A, Tabibian D, Francois P, Schrenzel J, Hafezi F. Antibacterial Efficacy of Accelerated Photoactivated Chromophore for Keratitis-Corneal Collagen Cross-linking (PACK-CXL). J Refract Surg. 2014. 30(12): 850-54. 10.3928/1081597X-20141118-01.
  28. Richoz O, Arba Mosquera S, Kling S, Hammer A, Magnago T, Bosch MM, Hafezi F. Determination of the excimer laser ablation rate in previously cross-linked corneas. J Refract Surg. 2014. 30(9): 628-32.
  29. Panos GD, Panos LD, Hafezi F, Gatzioufas Z. Ischemic Optic Neuropathy after a Long Airplane Flight: Coincidence or Rare Economy Class Syndrome Manifestation? Klin Monbl Augenheilkd. 2014. 231(4): 390-91. 10.1055/s-0034-1368250.
  30. Panos GD, Panos LD, Digklia A, Hafezi F, Gatzioufas Z. Unusual presentation of cerebral venous sinus thrombosis associated with contraceptive usage. J Ophthalmic Vis Res. 2014. 9(2): 281-4. 41812144181214.
  31. Panos GD, Hafezi F, Gatzioufas Z. Nonsensory effects of reduced corneal nerve density in congenital glaucoma. Invest Ophthalmol Vis Sci. 2014. 55(4): 2114. 10.1167/iovs.14-13946.
  32. Pajic B, Vastardis I, Pajic-Eggspuehler B, Gatzioufas Z, Hafezi F. Femtosecond laser versus mechanical microkeratome-assisted flap creation for LASIK: a prospective, randomized, paired-eye study. Clin Ophthalmol. 2014. 8: 1883-9. 10.2147/OPTH.S68124. 4181739.
  33. Hammer A, Tabibian D, Richoz O, Hafezi F. [Keratoconus treatment by corneal cross-linking (CLX)]. Rev Med Suisse. 2014. 10(433): 1263-5.
  34. Hammer A, Richoz O, Mosquera S, Tabibian D, Hoogewoud F, Hafezi F. Corneal biomechanical properties at different corneal collagen cross-linking (CXL) Irradiances. Invest Ophthalmol Vis Sci. 2014. 55(5): 2881-4. 10.1167/iovs.13-13748.
  35. Hafezi F, Tabibian D, Richoz O. Additive Effect of Repeated Corneal Collagen Cross-linking in Keratoconus. J Refract Surg. 2014. 30(10): 716-8. 10.3928/1081597X-20140903-03.
  36. Hafezi F, Randleman JB. PACK-CXL: defining CXL for infectious keratitis. J Refract Surg. 2014. 30(7): 438-9. 10.3928/1081597X-20140609-01.
  37. Hafezi F, Gatzioufas Z, Seiler TG, Seiler T. Corneal Collagen Cross-linking for Terrien Marginal Degeneration. J Refract Surg. 2014. 30(7): 1-3. 10.3928/1081597X-20140527-02.
  38. Gatzioufas Z, Panos GD, Brugnolli E, Hafezi F. Corneal topographical and biomechanical variations associated with hypothyroidism. J Refract Surg. 2014. 30(2): 78-9. 10.3928/1081597X-20140120-01.
  39. Gatzioufas Z, Labiris G, Hafezi F, Schnaidt A, Bajic B, Langenbucher A, Seitz B. Corneal sensitivity and morphology of the corneal subbasal nerve plexus in primary congenital glaucoma. Eye (Lond). 2014. 10.1038/eye.2014.4.
  40. Barbara R, Castillo JH, Hanna R-, Berkowitz E, Tiosano B, Barbara A. Keratoconus Expert Meeting 2014. Int J Keratoconus Ectatic Corn Dis. 2014. 3: 141-58.
  41. Spiess BM, Pot SA, Florin M, Hafezi F. Corneal collagen cross-linking (CXL) for the treatment of melting keratitis in cats and dogs: a pilot study. Vet Ophthalmol. 2013. 10.1111/vop.12027.
  42. Richoz O, Mavrakanas N, Pajic B, Hafezi F. Corneal Collagen Cross-Linking for Ectasia after LASIK and Photorefractive Keratectomy: Long-Term Results. Ophthalmology. 2013. 10.1016/j.ophtha.2012.12.027.
  43. Richoz O, Hammer A, Tabibian D, Gatzioufas Z, Hafezi F. The Biomechanical Effect of Corneal Collagen Cross-Linking (CXL) With Riboflavin and UV-A is Oxygen Dependent. Transl Vis Sci Technol. 2013. 2(7): 6. 10.1167/tvst.2.7.6. 3860351.
  44. Richoz O, Hafezi F. Modifications for Thin Corneas, in Corneal collagen cross-linking, Randleman B, Hafezi F, Editors. 2013, Slack Inc.: Thorofare, NJ, USA. 51-55.
  45. Richoz O, Gatzioufas Z, Hafezi F. Corneal Collagen Cross-Linking for the Treatment of Acanthamoeba Keratitis. Cornea. 2013. 10.1097/ICO.0b013e31829a689e.
  46. Richoz O, Gatzioufas Z, Francois P, Schrenzel J, Hafezi F. Impact of fluorescein on the antimicrobial efficacy of photoactivated riboflavin in corneal collagen cross-linking. J Refract Surg. 2013. 29(12): 842-5.
  47. Quenan S, Strueven V, Saxer N, Laffitte E, Kaya G, Krischer J, Hafezi F, Le Gal FA. Pruritic Acquired Nevus of Ota. Dermatology. 2013. 10.1159/000354604.
  48. Pot SA, Gallhofer NS, Walser-Reinhardt L, Hafezi F, Spiess BM. Treatment of bullous keratopathy with corneal collagen cross-linking in two dogs. Vet Ophthalmol. 2013. 10.1111/vop.12137.
  49. Pot SA, Gallhofer NS, Matheis FL, Voelter-Ratson K, Hafezi F, Spiess BM. Corneal collagen cross-linking as treatment for infectious and noninfectious corneal melting in cats and dogs: results of a prospective, nonrandomized, controlled trial. Vet Ophthalmol. 2013. 10.1111/vop.12090.
  50. Panos GD, Hafezi F, Gatzioufas Z. Visual outcomes after pituitary surgery. Swiss Med Wkly. 2013. 143: w13802. 10.4414/smw.2013.13802.
  51. Panos GD, Hafezi F, Gatzioufas Z. Pellucid marginal degeneration and keratoconus; Differential diagnosis by corneal topography. J Cataract Refract Surg. 2013. 39(6): 968. 10.1016/j.jcrs.2013.04.020.
  52. Panos GD, Hafezi F, Gatzioufas Z. Impact of Collagen Cross-Linking for Keratoconus on Corneal Sensitivity. Cornea. 2013. 32(7): E182-E83.
  53. Panos GD, Gatzioufas Z, Petropoulos IK, Dardabounis D, Thumann G, Hafezi F. Effect of ranibizumab on serous and vascular pigment epithelial detachments associated with exudative age-related macular degeneration. Drug Des Devel Ther. 2013. 7: 565-9. 10.2147/DDDT.S46610. 3712738.
  54. Pajic B, Latinovic S, Pajic-Eggspuehler B, Hafezi F, Muller J, Vukozavlzevic M, New Algorithm of LDV Crystalline Femtosecond Laser Leads to Very Smooth Surface and Epithelial Cut, in Jaypee's Video Atlas of Ophthalmic Surgery, Garg A, Editor. 2013, Jaypee Brothers, New Delhi, India.
  55. Pajic B, Hafezi F, Latinovic S, Pajic-Eggspuehler B, Muller J, Vukozavlzevic M, A Femtolasik Correction After Perforated Keratoplasty and Corneal Cross Linking In Keratoplasty and Corneal Cross Linking In, in Jaypee's Video Atlas of Ophthalmic Surgery, Garg A, Editor. 2013, Jaypee Brothers, New Delhi, India.
  56. Hoogewoud F, Gatzioufas Z, Hafezi F. Transitory topographical variations in keratoconus during pregnancy. J Refract Surg. 2013. 29(2): 144-6. 10.3928/1081597X-20130117-11.
  57. Hafezi F, Randleman B, Corneal Collagen Cross-Linking. 2013: Slack Inc, Thorofare, NJ.
  58. Hafezi F, Mavrakanas N. Corneal Collagen Cross-Linking for Postoperative Corneal Ectasia, in Corneal collagen cross-linking, Randleman B, Hafezi F, Editors. 2013, Slack Inc.: Thorofare, NJ, USA. 75-81.
  59. Hafezi F. Contributing factors to corneal deformation in air puff measurements. Invest Ophthalmol Vis Sci. 2013. 54(7). 10.1167/iovs.13-12747.
  60. Gatzioufas Z, Richoz O, Spoerl E, Hafezi F. Persistent corneal edema after collagen cross-linking for keratoconus. Am J Ophthalmol. 2013. 155(3): 610-1. 10.1016/j.ajo.2012.11.006.
  61. Gatzioufas Z, Richoz O, Brugnoli E, Hafezi F. Safety profile of high-fluence corneal collagen cross-linking for progressive keratoconus: preliminary results from a prospective cohort study. J Refract Surg. 2013. 29(12): 846-8. 10.3928/1081597X-20131023-03.
  62. Gatzioufas Z, Hafezi F, Kopsidas K, Thanos S. Dysfunctional uveoscleral pathway in a rat model of congenital glaucoma. J Physiol Pharmacol. 2013. 64(3): 393-7.
  63. Coskunseven E, Sharma DP, Jankov MR, 2nd, Kymionis GD, Richoz O, Hafezi F. Collagen copolymer toric phakic intraocular lens for residual myopic astigmatism after intrastromal corneal ring segment implantation and corneal collagen crosslinking in a 3-stage procedure for keratoconus. J Cataract Refract Surg. 2013. 39(5): 722-9. 10.1016/j.jcrs.2012.11.027.
  64. Bonhomme F, Hafezi F, Boehlen F, Habre W. Management of antithrombotic therapies in patients scheduled for eye surgery: A narrative review. Eur J Anaesthesiol. 2013. 10.1097/EJA.0b013e328360c442.
  65. Tschuor P, Hafezi F, Majo F. Iris Varix as a Cause of Late-Onset Inflammation after Implantation of a Phakic Iris Claw Lens. Klinische Monatsblatter Fur Augenheilkunde. 2012. 229(4): 462-63. 10.1055/s-0031-1299255.
  66. Richoz O, Schutz JS, Pajic B, Coskunseven E, Hafezi F. Crosslinking for recurrent keratoconus. Ophthalmology. 2012. 119(4): 878-78 e2. 10.1016/j.ophtha.2011.11.007.
  67. Perez Fornos A, Sommerhalder J, da Cruz L, Sahel JA, Mohand-Said S, Hafezi F, Pelizzone M. Temporal properties of visual perception on electrical stimulation of the retina. Invest Ophthalmol Vis Sci. 2012. 53(6): 2720-31. 10.1167/iovs.11-9344.
  68. Pajic B, Latinovic S, Hafezi F, Pajic-Eggspuehler B, Mrochen M, Fankhauser F. Lamellar corneal resection with LDV Crystal line femtosecond laser after penetrating keratoplasty, in Femtosecond laser technology, Gark A, Editor. 2012, Jaypee Brothers: Mumbai.
  69. Pajic B, Hafezi F, Pajic-Eggspuehler B, Mrochen M, Mueller J, Pajic D, Fankhauser F. Applanation-free femtosecond laser processing of the cornea, in Femtosecond laser technology, Gark A, Editor. 2012, Jaypee Brothers: Mumbai.
  70. Nicolas M, Abouzeid H, Deprez M, Hafezi F, Munier F, Othenin-Girard P, Majo F. Epithelial Ingrowth (EI) after LASIK or Automated Lamellar Therapeutic Keratoplasty (ALTK): an immunohistological study of 4 cases. Br J Ophthalmol. 2012. 96(7): 1043-46.
  71. Hafezi F, Koller T, Derhartunian V, Seiler T. Pregnancy may trigger late onset of keratectasia after LASIK. J Refract Surg. 2012. 28(4): 242-3. 10.3928/1081597X-20120401-07.
  72. Hafezi F. Significant visual increase following infectious keratitis after collagen cross-linking. J Refract Surg. 2012. 28(8): 587-8. 10.3928/1081597X-20120628-01.
  73. Chatzis N, Hafezi F. Progression of Keratoconus and Efficacy of Corneal Collagen Cross-linking in Children and Adolescents. J Refract Surg. 2012. 28(11): 753-8. 10.3928/1081597X-20121011-01.
  74. Barry MP, Dagnelie G, Argus IISG. Use of the Argus II retinal prosthesis to improve visual guidance of fine hand movements. Invest Ophthalmol Vis Sci. 2012. 53(9): 5095-101. 10.1167/iovs.12-9536. 3416020.
  75. Hayes S, Boote C, Kamma-Lorger CS, Rajan MS, Harris J, Dooley E, Hawksworth N, Hiller J, Terill NJ, Hafezi F, Brahma AK, Quantock AJ, Meek KM. Riboflavin/UVA collagen cross-linking-induced changes in normal and keratoconus corneal stroma. PLoS One. 2011. 6(8): e22405. 10.1371/journal.pone.0022405. 3151245.
  76. Hafezi F, Koller T, Vinciguerra P, Seiler T. Marked remodelling of the anterior corneal surface following collagen cross-linking with riboflavin and UVA. Br J Ophthalmol. 2011. 95(8): 1171-72.
  77. Hafezi F. November consultation #4. J Cataract Refract Surg. 2011. 37(11): 2085-6. 10.1016/j.jcrs.2011.09.023.
  78. Hafezi F. Limitation of collagen cross-linking with hypoosmolar riboflavin solution: failure in an extremely thin cornea. Cornea. 2011. 30(8): 917-9. 10.1097/ICO.0b013e31820143d1.
  79. Weiss JS, Workgroup FAPORI. Corneal dystrophies: molecular genetics to therapeutic intervention--Fifth ARVO/Pfizer Ophthalmics Research Institute Conference. Invest Ophthalmol Vis Sci. 2010. 51(11): 5391-402. 51/11/5391 [pii] 10.1167/iovs.09-4746.
  80. Vinciguerra P, Albe E, Mahmoud AM, Trazza S, Hafezi F, Roberts CJ. Intra- and Postoperative Variation in Ocular Response Analyzer Parameters in Keratoconic Eyes After Corneal Cross-Linking. J Refract Surg. 2010: 1-8. 10.3928/1081597X-20100331-01.
  81. Hafezi F, Seiler T, Iseli HP. Light-adjustable lens complication. Ophthalmology. 2010. 117(4): 848-48 e1. S0161-6420(09)01444-4 [pii] 10.1016/j.ophtha.2009.12.019.
  82. Hafezi F, Seiler T. Persistent subepithelial haze in thin-flap LASIK. J Refract Surg. 2010. 26(3): 222-5. 10.3928/1081597X-20090930-02.
  83. Hafezi F, Moesen I, Carels G, Mooy C, Paridaens D. [Waldenstrom's macroglobulinaemia of the lacrimal gland in a patient with sarcoidosis]. Ophthalmology. 2010. 107(1): 60-3. 10.1007/s00347-009-2010-5.
  84. Hafezi F, Majo F, El Danasoury AM. Effect of the Direct Application of Riboflavin and UVA on the Visian Implantable Collamer Lens. J Refract Surg. 2010: 1-4. 10.3928/1081597X-20100415-01.
  85. Hafezi F, Dejica P, Majo F. Modified corneal collagen crosslinking reduces corneal oedema and diurnal visual fluctuations in Fuchs dystrophy. Br J Ophthalmol. 2010. 94(5): 660-1. 94/5/660 [pii] 10.1136/bjo.2009.162479.
  86. Hafezi F. Tobacco smoking and its impact on corneal biomechanics. Invest Ophthalmol Vis Sci. 2010. 51(12): 6892. 51/12/6892 [pii] 10.1167/iovs.09-4735.
  87. Bertschinger DR, Hashemi K, Hafezi F, Majo F. Infections after PRK could have a happy ending: a series of three cases. Klin Monbl Augenheilkd. 2010. 227(4): 315-8. 10.1055/s-0029-1245222.
  88. Akda F, Hafezi F, Heule-Dieleman HA, van den Bosch WA, Luyten GP, Tanghe HL, Paridaens D. [Orbital metastases of breast cancer. Radiologic features]. Ophthalmology. 2010. 107(8): 728-32. 10.1007/s00347-009-2122-y.
  89. Vijlbrief JW, Hafezi F, Paridaens D. [Anterior surface breakdown following evisceration : "Classic", "scleral modification", and "scleral patch techniques"]. Ophthalmology. 2009: Epub ahead of print. 10.1007/s00347-009-1988-z.
  90. Paridaens AD, Hafezi F, van den Bosch WA, Video Atlas of Oculoplastic Surgery, Paridaens AD, van den Bosch WA, Editors. 2009, Rotterdam Eye Clinic, Rotterdam, The Netherlands: Rotterdam, The Netherlands.
  91. Koller T, Iseli HP, Hafezi F, Vinciguerra P, Seiler T. Scheimpflug imaging of corneas after collagen cross-linking. Cornea. 2009. 28(5): 510-5. 10.1097/ICO.0b013e3181915943.
  92. Iseli HP, Hafezi F, Mrochen M, Seiler T. Estado actual de la reticulación del colágeno corneal, in Técnicas de modelado corneal: desde la ortoqueratologia hasta el cross-linking, Cezón Prieto J, Editor. 2009, Sociedad Española de Cirurgia Ocular Implanto-Refractiva: Madrid. 381-86.
  93. Hafezi F, Mrochen M, Iseli HP, Seiler T. Collagen crosslinking with ultraviolet-A and hypoosmolar riboflavin solution in thin corneas. J Cataract Refract Surg. 2009. 35(4): 621-4. S0886-3350(09)00062-5 [pii] 10.1016/j.jcrs.2008.10.060.
  94. Hafezi F. Cross-Linking of Corneal Collagen with UVA and Riboflavin for the Treatment of Corneal Disease. Iran J Ophthalmol. 2009. 21(2): 3-12.
  95. Hafezi F. Smoking and corneal biomechanics. Ophthalmology. 2009. 116(11): 2259 e1. S0161-6420(09)00848-3 [pii] 10.1016/j.ophtha.2009.07.039.
  96. Coskunseven E, Jankov MR, 2nd, Hafezi F, Atun S, Arslan E, Kymionis GD. Effect of treatment sequence in combined intrastromal corneal rings and corneal collagen crosslinking for keratoconus. J Cataract Refract Surg. 2009. 35(12): 2084-91. S0886-3350(09)00786-X [pii] 10.1016/j.jcrs.2009.07.008.
  97. Coskunseven E, Jankov MR, 2nd, Hafezi F. Contralateral eye study of corneal collagen cross-linking with riboflavin and UVA irradiation in patients with keratoconus. J Refract Surg. 2009. 25(4): 371-6.
  98. Berguiga M, Uffer S, Hafezi F, Majo F. Pseudomonas cepacia (PC) contamination of a cornea conservated in organ culture. Klin Monatsbl Augenheilkd. 2009. 226(4): 348-9. 10.1055/s-0028-1109284.
  99. Lindstedt EW, Hafezi F, Veckeneer MA, Mooy CM, Paridaens D. [Orbital inflammation due to intraocular malignant melanoma]. Klin Monatsbl Augenheilkd. 2008. 225(10): 888-9. 10.1055/s-2008-1027719.
  100. Jankov II MR, Hafezi F, Beko M, Ignjatovic Z, Djurovic B, Markovic V, Schor P. [Corneal Cross-linking for the treatment of keratoconus: preliminary results.]. Arq Bras Oftalmol. 2008. 71(6): 813-8. S0004-27492008000600009 [pii].
  101. Iseli HP, Thiel MA, Hafezi F, Kampmeier J, Seiler T. Ultraviolet A/riboflavin corneal cross-linking for infectious keratitis associated with corneal melts. Cornea. 2008. 27(5): 590-4.
  102. Hafezi F, Seiler T. Reply: Crosslinking for iatrogenic keratectasia after LASIK and for keratoconus. J Cataract Refract Surg. 2008. 34(6): 879.
  103. Hafezi F, Iseli HP. Pregnancy-related exacerbation of iatrogenic keratectasia despite corneal collagen crosslinking. J Cataract Refract Surg. 2008. 34(7): 1219-21. S0886-3350(08)00365-9 [pii] 10.1016/j.jcrs.2008.02.036.
  104. Bleyen I, Hafezi F, de Faber JT, Paridaens D. [Strabismus correction as an alternative treatment to evisceration and enucleation for artificial eye prosthesis intolerance in atrophic eyes.]. Ophthalmologe. 2008.
  105. Stanescu D, Iseli HP, Schwerdtfeger K, Ittner LM, Reme CE, Hafezi F. Continuous expression of the homeobox gene Pax6 in the ageing human retina. Eye. 2007. 21(1): 90-3.
  106. Paarlberg JC, den Hollander JC, Hafezi F, Paridaens D. [Adenoid cystic carcinoma of the upper eyelid.]. Ophthalmologe. 2007.
  107. Ittner LM, Schwerdtfeger K, Kunz TH, Muff R, Husmann K, Grimm C, Hafezi F, Lang KS, Kurrer MO, Gotz J, Born W, Fischer JA. Transgenic mice with ocular overexpression of an adrenomedullin receptor reflect human acute angle-closure glaucoma. Clin Sci (Lond). 2007.
  108. Hafezi F, Paridaens D. [Unusual orbital trauma with diplopia]. Ophthalmologe. 2007. 104(2): 163-4.
  109. Hafezi F, Kanellopoulos J, Wiltfang R, Seiler T. Corneal collagen crosslinking with riboflavin and ultraviolet A to treat induced keratectasia after laser in situ keratomileusis. J Cataract Refract Surg. 2007. 33(12): 2035-40.
  110. Seiler T, Hafezi F, Iseli HP, Koller T, Alkara N. Reoperations after LASIK. Klin Monatsbl Augenheilkd. 2006. 223(6): 509-12.
  111. Seiler T, Hafezi F. Corneal cross-linking-induced stromal demarcation line. Cornea. 2006. 25(9): 1057-9.
  112. Mrochen M, Hafezi F, Jankov M, Seiler T. Ablation profiles in corneal laser surgery. Current and future concepts. Ophthalmologe. 2006. 103(3): 175-83.
  113. Mrochen M, Hafezi F, Iseli HP, Loffler J, Seiler T. Nomograms for the improvement of refractive outcomes. Ophthalmologe. 2006. 103(4): 331-8.
  114. Koller T, Iseli HP, Hafezi F, Mrochen M, Seiler T. Q-factor customized ablation profile for the correction of myopic astigmatism. J Cataract Refract Surg. 2006. 32(4): 584-9.
  115. Hafezi F, Jankov M, Mrochen M, Wullner C, Seiler T. Customized ablation algorithm for the treatment of steep central islands after refractive laser surgery. J Cataract Refract Surg. 2006. 32(5): 717-21.
  116. Hafezi F, Bockholts D, van den Bosch WA, Paridaens AD. [Giant mucocele of all paranasal sinuses with massive bilateral globe displacement]. Ophthalmologe. 2006. 103(4): 340-1.
  117. Ittner LM, Wurdak H, Schwerdtfeger K, Kunz T, Ille F, Leveen P, Hjalt TA, Suter U, Karlsson S, Hafezi F, Born W, Sommer L. Compound developmental eye disorders following inactivation of TGFbeta signaling in neural-crest stem cells. J Biol (BMC Biol). 2005. 4(3): 11.
  118. Iseli HP, Bueeler M, Hafezi F, Seiler T, Mrochen M. Dependence of wave front refraction on pupil size due to the presence of higher order aberrations. Eur J OphthalmoL. 2005. 15(6): 680-7.
  119. Hafezi F, Mrochen M, Seiler T. Two-step procedure to enlarge small optical zones after photorefractive keratectomy for high myopia. J Cataract Refract Surg. 2005. 31(12): 2254-6.
  120. Hafezi F, Iseli HP, Seiler T. Automated anterior lamellar keratoplasty for the management of complications in refractive surgery, in Surgical techniques in anterior and posterior lamellar corneal surgery, John T, Editor. 2005, Slack Inc.: New York.
  121. Mrochen M, Bueeler M, Iseli HP, Hafezi F, Seiler T. Transferring Wavefront Measurements Into Corneal Ablations: An Overview of Related Topics. J Refract Surg. 2004. 20: S580-84.
  122. Iseli HP, Mrochen M, Hafezi F, Seiler T. Clinical photoablation with a 500-Hz scanning spot excimer laser. J Refract Surg. 2004. 20(6): 831-4.
  123. Seiler T, Iseli HP, Hafezi F, Mrochen M. Supernormales Sehvermögen. Dtsch Ärzteblatt International. 2003. 100(11): 700-04.
  124. Reme CE, Grimm C, Hafezi F, Iseli HP, Wenzel A. Why study rod cell death in retinal degenerations and how? Doc Ophthalmol. 2003. 106(1): 25-9.
  125. Neeracher B, Iseli HP, Ganter C, Saupe N, Hafezi F. Hypopigmentation of the fundus oculi and pulmonary fibrosis. Ophthalmologe. 2003. 100(6): 480-81.
  126. Mrochen M, Jankov M, Iseli HP, Hafezi F, Seiler T. Retinal imaging aberrometry - principles and application of the Tscherning aberrometer, in Wavefront Customized Visual Correction: The Quest for Super Vision II, MacRae S, Krueger RR, Applegate RA, Editors. 2003, Slack Incorporated: New York. 137-43.
  127. Iseli HP, Hafezi F, Mojon DS. Conservative treatment of vertical diplopia in a patient with silent sinus syndrome. Ophthalmologica. 2003. 217(4): 308-9.
  128. Hafezi F, Mrochen M, Fankhauser F, 2nd, Seiler T. Anterior lamellar keratoplasty with a microkeratome: a method for managing complications after refractive surgery. J Refract Surg. 2003. 19(1): 52-7.
  129. Wenzel A, Iseli HP, Fleischmann A, Hafezi F, Grimm C, Wagner EF, Reme CE. Fra-1 substitutes for c-Fos in AP-1-mediated signal transduction in retinal apoptosis. J Neurochem. 2002. 80(6): 1089-94.
  130. Iseli HP, Wenzel A, Hafezi F, Reme CE, Grimm C. Light damage susceptibility and RPE65 in rats. Exp Eye Res. 2002. 75(4): 407-13.
  131. Wenzel A, Reme CE, Williams TP, Hafezi F, Grimm C. The Rpe65 Leu450Met variation increases retinal resistance against light-induced degeneration by slowing rhodopsin regeneration. J Neurosci. 2001. 21(1): 53-8.
  132. Wenzel A, Grimm C, Seeliger MW, Jaissle G, Hafezi F, Kretschmer R, Zrenner E, Reme CE. Prevention of photoreceptor apoptosis by activation of the glucocorticoid receptor. Invest Ophthalmol Vis Sci. 2001. 42(7): 1653-9.
  133. Kniestedt C, Hafezi F, Seiler T. Ultrasound biomicroscopical diagnosis of traumatic choroidal effusion without cyclodialysis. Ophthalmologe. 2001. 98(7): 656-59.
  134. Keller C, Grimm C, Wenzel A, Hafezi F, Reme C. Protective effect of halothane anesthesia on retinal light damage: inhibition of metabolic rhodopsin regeneration. Invest Ophthalmol Vis Sci. 2001. 42(2): 476-80.
  135. Hafezi F, Welzl-Hinterkorner E, Tholen AM. Idiopathic sclerochoroidal calcification - a case report. Klin Monatsbl Augenheilkd. 2001. 218(3): 197-200.
  136. Grimm C, Wenzel A, Williams T, Rol P, Hafezi F, Reme C. Rhodopsin-mediated blue-light damage to the rat retina: effect of photoreversal of bleaching. Invest Ophthalmol Vis Sci. 2001. 42(2): 497-505.
  137. Grimm C, Wenzel A, Behrens A, Hafezi F, Wagner EF, Reme CE. AP-1 mediated retinal photoreceptor apoptosis is independent of N-terminal phosphorylation of c-Jun. Cell Death Differ. 2001. 8(8): 859-67.
  138. Wenzel A, Grimm C, Marti A, Kueng-Hitz N, Hafezi F, Niemeyer G, Reme CE. c-Fos controls the "private pathway" of light-induced apoptosis of retinal photoreceptors. J Neurosci. 2000. 20(1): 81-8.
  139. Reme CE, Grimm C, Hafezi F, Wenzel A, Williams TP. Apoptosis in the Retina: The Silent Death of Vision. Physiology (former News Physiol Sci). 2000. 15: 120-24.
  140. Kueng-Hitz N, Grimm C, Lansel N, Hafezi F, He L, Fox DA, Reme CE, Niemeyer G, Wenzel A. The retina of c-fos-/- mice: electrophysiologic, morphologic and biochemical aspects. Invest Ophthalmol Vis Sci. 2000. 41(3): 909-16.
  141. Hafezi F, Grimm C, Simmen BC, Wenzel A, Reme CE. Molecular ophthalmology: an update on animal models for retinal degenerations and dystrophies. Br J Ophthalmol. 2000. 84(8): 922-7.
  142. Hafezi F, Boltshauser E, Landau K. Pronounced physiological pupillary hippus. Klin Monatsbl Augenheilkd. 2000. 216(2): 118-19.
  143. Grimm C, Wenzel A, Hafezi F, Yu S, Redmond TM, Reme CE. Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration. Nat Genet. 2000. 25(1): 63-6.
  144. Grimm C, Wenzel A, Hafezi F, Reme CE. Gene expression in the mouse retina: the effect of damaging light. Mol Vis. 2000. 6: 252-60.
  145. Fleischmann A, Hafezi F, Elliott C, Reme CE, Ruther U, Wagner EF. Fra-1 replaces c-Fos-dependent functions in mice. Genes Dev. 2000. 14(21): 2695-700.
  146. Abegg M, Hafezi F, Wenzel A, Grimm C, Reme CE. Therapeutic strategies in RP (retinitis pigmentosa): light at the end of the tunnel? Klin Monatsbl Augenheilkd. 2000. 216(2): 83-9. 10.1055/s-2000-10523.
  147. Reme CE, Wolfrum U, Imsand C, Hafezi F, Williams TP. Photoreceptor autophagy: effects of light history on number and opsin content of degradative vacuoles. Invest Ophthalmol Vis Sci. 1999. 40(10): 2398-404.
  148. Lansel N, Hafezi F, Marti A, Hegi M, Reme C, Niemeyer G. The mouse ERG before and after light damage is independent of p53. Doc Ophthalmol. 1999. 96(4): 311-20.
  149. Hafezi F, Marti A, Grimm C, Wenzel A, Reme CE. Differential DNA binding activities of the transcription factors AP-1 and Oct-1 during light-induced apoptosis of photoreceptors. Vision Res. 1999. 39(15): 2511-8.
  150. Hafezi F, Grimm C, Wenzel A, Abegg M, Yaniv M, Reme CE. Retinal photoreceptors are apoptosis-competent in the absence of JunD/AP-1. Cell Death Differ. 1999. 6(10): 934-6.
  151. Hafezi F, Abegg M, Wenzel A, Grimm C, Remé CE. Lichtschäden des Auges: ein Überblick, in Risikofaktoren für Augenerkrankungen, Erb C, Flammer J, Editors. 1999, Hans Huber: Bern, Göttingen, Toronto, Seattle. 277-83.
  152. Remé CE, Hafezi F, Marti A, Munz K, Reinboth JJ. Light damage to retina and pigment epithelium, in The Retinal Pigment Epithelium, current aspects of function and disease, Marmor MF, Wolfensberger T, Editors. 1998, Oxford University Press: Oxford. 563-86.
  153. Reme CE, Grimm C, Hafezi F, Marti A, Wenzel A. Apoptotic cell death in retinal degenerations, in Prog Retin Eye Res, Osborne NN, Chader GJ, Editors. 1998, Pergamon Press: New York, Tokyo. 443-64. Impact factor: 7.5
  154. Remé CE, Bush R, Hafezi F, Wenzel A, Grimm C. Photostasis and beyond: where adaptation ends, in Photostasis and related phenomena, Williams TP, Thistle AB, Editors. 1998, Plenum Press: New York. 199-206.
  155. Marti A, Hafezi F, Lansel N, Hegi ME, Wenzel A, Grimm C, Niemeyer G, Reme CE. Light-induced cell death of retinal photoreceptors in the absence of p53. Invest Ophthalmol Vis Sci. 1998. 39(5): 846-9.
  156. Hafezi F, Wenzel A, Grimm C, Reme CE. Retinal degeneration, apoptosis and the c-fos gene. Neuro-Ophthalmology. 1998. 20(3): 143-48.
  157. Hafezi F, Reinboth JJ, Wenzel A, Munz K, Reme CE. HPETE, an arachidonic acid metabolite, induces apoptosis in the rat retina in vitro. Klin Monatsbl Augenheilkd. 1998. 212(6): 469-72.
  158. Hafezi F, Marti A, Steinbach JP, Munz K, Aguzzi A, Remé CE. Light-induced retinal degeneration is prevented in mice lacking c-fos, in Degenerative retinal diseases, LaVail MM, Hollyfield JG, Anderson RE, Editors. 1998, Plenum Press: New York. 193-98.
  159. Hafezi F, Abegg M, Grimm C, Wenzel A, Munz K, Sturmer J, Farber DB, Reme CE. Retinal degeneration in the rd mouse in the absence of c-fos. Invest Ophthalmol Vis Sci. 1998. 39(12): 2239-44.
  160. Remé CE, Hafezi F, Grimm C, Wenzel A. UV- und Lichtschäden des Auges - wie kann man sich schützen?, in Physikalische Therapiemassnahmen in der Dermatologie, Dummer R, Panizzon R, Burg G, Editors. 1997, Blackwell Wissenschaftsverlag: Berlin. 200-09.
  161. Hafezi F, Steinbach JP, Marti A, Munz K, Wang ZQ, Wagner EF, Aguzzi A, Reme CE. The absence of c-fos prevents light-induced apoptotic cell death of photoreceptors in retinal degeneration in vivo. Nat Med. 1997. 3(3): 346-9.
  162. Hafezi F, Marti A, Munz K, Remé CE. Early events in light-induced apoptosis of photoreceptors and pigment epithelium of rats in vivo, in Les Seminaires ophthalmologiques Ipsen,. 1997, Editions Irvinn: Paris. 13-17.
  163. Hafezi F, Marti A, Munz K, Reme CE. Light-induced apoptosis: differential timing in the retina and pigment epithelium. Exp Eye Res. 1997. 64(6): 963-70.
  164. Reme C, Reinboth J, Clausen M, Hafezi F. Light damage revisited: converging evidence, diverging views? Graefes Arch Clin Exp Ophthalmol. 1996. 234(1): 2-11.
  165. Reme CE, Weller M, Szczesny P, Munz K, Hafezi F, Reinboth JJ, Clausen M. Light-induced apoptosis in the rat retina in vivo: morphological features, threshold and time course, in Degenerative diseases of the retina. Anderson RE, LaVail MM, Hollyfield JG, Editors. 1995, Plenum Press: New York. 19-25.
  166. Bohlen LM, de Courten M, Hafezi F, Shaw S, Riesen W, Weidmann P. Insulin sensitivity and atrial natriuretic factor during beta-receptor modulation with celiprolol in normal subjects. J Cardiovasc Pharmacol. 1994. 23(6): 877-83.