< BackResearch FacultyQifa Zhou, PhD

Qifa Zhou, PhD

Dr-Qifa-Zhou

Professor of Ophthalmology, Biomedical Engineering

Research Topics:

High Frequency Ultrasound
Multimodal Imaging
Ophthalmic Elastography
Integration of Ultrasound and OCT technology
Ultrasonic Retinal and Brain Stimulation
Ultrasonic Drug Delivery
3D printing technology

Clinical Interests:

Retinal Degenerative Diseases
Corneal Diseases
Glaucoma

Biography:

Dr. Qifa Zhou has developed high frequency ultrasound composite and single crystal ultrasound transducers and arrays, fabricated by MEMS technology for various biomedical imaging applications. His lab is the first to have developed high sensitivity PMN-PT single crystal transducers for ultrasound and photoacoustic imaging, including intravascular imaging, cancer imaging and ophthalmic imaging. He and his collaborators have been developing a novel imaging tool for characterizing elastic properties of retinal and corneal tissue by acoustic radiation force induced optical coherence electrography. His lab is also investigating high resolution ultrasonic elastographic imaging techniques using high frequency ultrasound. He is also actively exploring ultrasonic mediated therapeutic technology including trans-sclera drug delivery, as well as ultrasound for retinal and brain stimulation.

Education:

Xi’an Jiaotong University, Electronic Engineering, PhD, 1993

The Penn State University, Materials Research Institute, Postdoctoral Fellow, 2000

Awards:

SPIE Fellow (the international society for optics and photonics), 2014

AIMBE Fellow (American Institute for Medical and Biological Engineering), 2014

IEEE Ultrasound, Ferroelectric, and Frequency Control Society, International Ultrasound Symposium, student paper competition award,2010

Croucher Fellowship of Croucher Foundation, 1998

Publications:

  1. Lei H, Johnson LA, Liu S, Moons DS, Ma T, Zhou Q, Rice MD, Ni J, Wang X, Higgins PD, Xu G. Characterizing Intestinal Inflammation and Fibrosis in Crohn's Disease by Photoacoustic Imaging: Feasibility Study. Biomed Opt Express. 2016 Jul 1;7(7):2837-48
  2. Qu Y, Ma T, He Y, Zhu J, Dai C, Yu M, Huang S, Lu F, Shung KK, Zhou Q, Chen Z. Acoustic Radiation Force Optical Coherence Elastography of Corneal Tissue. IEEE J Sel Top Quantum Electron. 2016 May-Jun;22(3)
  3. Zhu B, Xu J, Li Y, Wang T, Xiong K, Lee C, Yang X, Shiiba M, Takeuchi S, Zhou Q, Shung KK. Micro-Particle Manipulation by Single Beam Acoustic Tweezers Based on Hydrothermal Pzt Thick Film. AIP Adv. 2016 Mar;6(3):035102
  4. Packard RR, Zhang X, Luo Y, Ma T, Jen N, Ma J, Demer LL, Zhou Q, Sayre JW, Li R, Tai YC, Hsiai TK. Two-Point Stretchable Electrode Array for Endoluminal Electrochemical Impedance Spectroscopy Measurements of Lipid-Laden Atherosclerotic Plaques. Ann Biomed Eng. 2016 Feb 8
  5. Fei C, Chiu CT, Chen X, Chen Z, Ma J, Zhu B, Shung KK, Zhou Q. Ultrahigh Frequency (100 Mhz-300 Mhz) Ultrasonic Transducers for Optical Resolution Medical Imagining. Sci Rep. 2016;6:28360
  6. Zhu J, Qu Y, Ma T, Li R, Du Y, Huang S, Shung KK, Zhou Q, Chen Z. Imaging and Characterizing Shear Wave and Shear Modulus under Orthogonal Acoustic Radiation Force Excitation Using Oct Doppler Variance Method. Opt Lett. 2015 May 1;40(9):2099-102
  7. Zhu B, Zhang Z, Ma T, Yang X, Li Y, Shung KK, Zhou Q. (100)-Textured Knn-Based Thick Film with Enhanced Piezoelectric Property for Intravascular Ultrasound Imaging. Appl Phys Lett. 2015 Apr 27;106(17):173504
  8. Yang JM, Li C, Chen R, Rao B, Yao J, Yeh CH, Danielli A, Maslov K, Zhou Q, Shung KK, Wang LV. Optical-Resolution Photoacoustic Endomicroscopy in Vivo. Biomed Opt Express. 2015 Mar 1;6(3):918-32
  9. Yang JM, Favazza C, Yao J, Chen R, Zhou Q, Shung KK, Wang LV. Three-Dimensional Photoacoustic Endoscopic Imaging of the Rabbit Esophagus. PLoS One. 2015;10(4):e0120269
  10. Sun K, Gao Z, Gui P, Wang R, Oguzman I, Xu X, Vasanth K, Zhou Q, Shung KK. A 180-Vpp Integrated Linear Amplifier for Ultrasonic Imaging Applications in a High-Voltage Cmos Soi Technology. IEEE Trans Circuits Syst II Express Briefs. 2015 Feb;62(2):149-53
  11. Piao Z, Ma T, Li J, Wiedmann MT, Huang S, Yu M, Kirk Shung K, Zhou Q, Kim CS, Chen Z. High Speed Intravascular Photoacoustic Imaging with Fast Optical Parametric Oscillator Laser at 1.7 Mum. Appl Phys Lett. 2015 Aug 24;107(8):083701
  12. Ning B, Sun N, Cao R, Chen R, Kirk Shung K, Hossack JA, Lee JM, Zhou Q, Hu S. Ultrasound-Aided Multi-Parametric Photoacoustic Microscopy of the Mouse Brain. Sci Rep. 2015;5:18775
  13. Ning B, Kennedy MJ, Dixon AJ, Sun N, Cao R, Soetikno BT, Chen R, Zhou Q, Kirk Shung K, Hossack JA, Hu S. Simultaneous Photoacoustic Microscopy of Microvascular Anatomy, Oxygen Saturation, and Blood Flow. Opt Lett. 2015 Mar 15;40(6):910-3
  14. Ma T, Yu M, Li J, Munding CE, Chen Z, Fei C, Shung KK, Zhou Q. Multi-Frequency Intravascular Ultrasound (Ivus) Imaging. IEEE Trans Ultrason Ferroelectr Freq Control. 2015 Jan;62(1):97-107
  15. Ma T, Yu M, Li J, Munding CE, Chen Z, Fei C, Shung KK, Zhou Q. Erratum: Multi-Frequency Intravascular Ultrasound (Ivus) Imaging. IEEE Trans Ultrason Ferroelectr Freq Control. 2015 Mar;62(3):604
  16. Ma T, Qian X, Chiu CT, Yu M, Jung H, Tung YS, Shung KK, Zhou Q. High-Resolution Harmonic Motion Imaging (Hr-Hmi) for Tissue Biomechanical Property Characterization. Quant Imaging Med Surg. 2015 Feb;5(1):108-17
  17. Ma J, Martin KH, Li Y, Dayton PA, Shung KK, Zhou Q, Jiang X. Design Factors of Intravascular Dual Frequency Transducers for Super-Harmonic Contrast Imaging and Acoustic Angiography. Phys Med Biol. 2015 May 7;60(9):3441-57
  18. Li Y, Ma J, Martin K, Yu M, Ma T, Dayton P, Jiang X, Shung K, Zhou Q. An Integrated System for Super-Harmonic Contrast-Enhanced Ultrasound Imaging: Design and Intravascular Phantom Imaging Study. IEEE Trans Biomed Eng. 2015 Dec 8
  19. Li J, Minami H, Steward E, Ma T, Mohar D, Robertson C, Shung K, Zhou Q, Patel P, Chen Z. Optimal Flushing Agents for Integrated Optical and Acoustic Imaging Systems. J Biomed Opt. 2015 May;20(5):56005
  20. Li J, Ma T, Mohar D, Steward E, Yu M, Piao Z, He Y, Shung KK, Zhou Q, Patel PM, Chen Z. Ultrafast Optical-Ultrasonic System and Miniaturized Catheter for Imaging and Characterizing Atherosclerotic Plaques in Vivo. Sci Rep. 2015;5:18406
  21. Lee C, Lee D, Zhou Q, Kim J, Kim C. Real-Time near-Infrared Virtual Intraoperative Surgical Photoacoustic Microscopy. Photoacoustics. 2015 Sep;3(3):100-6
  22. Hwang JY, Kang BJ, Lee C, Kim HH, Park J, Zhou Q, Shung KK. Non-Contact Acoustic Radiation Force Impulse Microscopy Via Photoacoustic Detection for Probing Breast Cancer Cell Mechanics. Biomed Opt Express. 2015 Jan 1;6(1):11-22
  23. Hui J, Yu Q, Ma T, Wang P, Cao Y, Bruning RS, Qu Y, Chen Z, Zhou Q, Sturek M, Cheng JX, Chen W. High-Speed Intravascular Photoacoustic Imaging at 1.7 Mum with a Ktp-Based Opo. Biomed Opt Express. 2015 Nov 1;6(11):4557-66
  24. He Z, Zheng F, Ma Y, Kim HH, Zhou Q, Shung KK. A Sidelobe Suppressing near-Field Beamforming Approach for Ultrasound Array Imaging. J Acoust Soc Am. 2015 May;137(5):2785-90
  25. Fei C, Ma J, Chiu CT, Williams JA, Fong W, Chen Z, Zhu B, Xiong R, Shi J, Hsiai TK, Shung KK, Zhou Q. Design of Matching Layers for High-Frequency Ultrasonic Transducers. Appl Phys Lett. 2015 Sep 21;107(12):123505
  26. Zhou Q, Lam KH, Zheng H, Qiu W, Shung KK. Piezoelectric Single Crystals for Ultrasonic Transducers in Biomedical Applications. Prog Mater Sci. 2014 Oct 1;66:87-111
  27. Zhang J, Huang W, Zhou Q. Reflectance Variation within the in-Chlorophyll Centre Waveband for Robust Retrieval of Leaf Chlorophyll Content. PLoS One. 2014;9(11):e110812
  28. Yang JM, Li C, Chen R, Zhou Q, Shung KK, Wang LV. Catheter-Based Photoacoustic Endoscope. J Biomed Opt. 2014 Jun;19(6):066001
  29. Wang P, Ma T, Slipchenko MN, Liang S, Hui J, Shung KK, Roy S, Sturek M, Zhou Q, Chen Z, Cheng JX. High-Speed Intravascular Photoacoustic Imaging of Lipid-Laden Atherosclerotic Plaque Enabled by a 2-Khz Barium Nitrite Raman Laser.Sci Rep. 2014;4:6889
  30. Qian M, Niu L, Wong KK, Abbott D, Zhou Q, Zheng H. Pulsatile Flow Characterization in a Vessel Phantom with Elastic Wall Using Ultrasonic Particle Image Velocimetry Technique: The Impact of Vessel Stiffness on Flow Dynamics. IEEE Trans Biomed Eng. 2014 Sep;61(9):2444-50
  31. Qi W, Li R, Ma T, Kirk Shung K, Zhou Q, Chen Z. Confocal Acoustic Radiation Force Optical Coherence Elastography Using a Ring Ultrasonic Transducer. Appl Phys Lett. 2014 Mar 24;104(12):123702
  32. Ma T, Zhang X, Chiu CT, Chen R, Kirk Shung K, Zhou Q, Jiao S. Systematic Study of High-Frequency Ultrasonic Transducer Design for Laser-Scanning Photoacoustic Ophthalmoscopy. J Biomed Opt. 2014 Jan;19(1):16015
  33. Liang S, Ma T, Jing J, Li X, Li J, Shung KK, Zhou Q, Zhang J, Chen Z. Trimodality Imaging System and Intravascular Endoscopic Probe: Combined Optical Coherence Tomography, Fluorescence Imaging and Ultrasound Imaging. Opt Lett. 2014 Dec 1;39(23):6652-5
  34. Li Y, Lee C, Chen R, Zhou Q, Shung KK. A Feasibility Study of in Vivo Applications of Single Beam Acoustic Tweezers. Appl Phys Lett. 2014 Oct 27;105(17):173701
  35. Li X, Ma T, Tian J, Han P, Zhou Q, Shung KK. Micromachined Pin-Pmn-Pt Crystal Composite Transducer for High-Frequency Intravascular Ultrasound (Ivus) Imaging. IEEE Trans Ultrason Ferroelectr Freq Control. 2014 Jul;61(7):1171-8
  36. Li X, Li J, Jing J, Ma T, Liang S, Zhang J, Mohar D, Raney A, Mahon S, Brenner M, Patel P, Shung KK, Zhou Q, Chen Z. Integrated Ivus-Oct Imaging for Atherosclerotic Plaque Characterization. IEEE J Sel Top Quantum Electron. 2014 Mar;20(2):7100108
  37. Li L, Yeh C, Hu S, Wang L, Soetikno BT, Chen R, Zhou Q, Shung KK, Maslov KI, Wang LV. Fully Motorized Optical-Resolution Photoacoustic Microscopy. Opt Lett. 2014 Apr 1;39(7):2117-20
  38. Li J, Li X, Mohar D, Raney A, Jing J, Zhang J, Johnston A, Liang S, Ma T, Shung KK, Mahon S, Brenner M, Narula J, Zhou Q,Patel PM, Chen Z. Integrated Ivus-Oct for Real-Time Imaging of Coronary Atherosclerosis. JACC Cardiovasc Imaging. 2014 Jan;7(1):101-3
  39. Li C, Yang JM, Chen R, Yeh CH, Zhu L, Maslov K, Zhou Q, Shung KK, Wang LV. Urogenital Photoacoustic Endoscope. Opt Lett. 2014 Mar 15;39(6):1473-6
  40. Jansen K, van der Steen AF, Wu M, van Beusekom HM, Springeling G, Li X, Zhou Q, Shung KK, de Kleijn DP, van Soest G. Spectroscopic Intravascular Photoacoustic Imaging of Lipids in Atherosclerosis. J Biomed Opt. 2014 Feb;19(2):026006
  41. Chen R, Cabrera-Munoz NE, Lam KH, Hsu HS, Zheng F, Zhou Q, Shung KK. Pmn-Pt Single-Crystal High-Frequency Kerfless Phased Array. IEEE Trans Ultrason Ferroelectr Freq Control. 2014 Jun;61(6):1033-41
  42. Zhu B, Chan NY, Dai J, Shung KK, Takeuchi S, Zhou Q. New Fabrication of High-Frequency (100-Mhz) Ultrasound Pzt Film Kerfless Linear Array. IEEE Trans Ultrason Ferroelectr Freq Control. 2013 Apr;60(4):854-7
  43. Zhan J, Lin H, Shen Q, Zhou Q, Zhao Y. Potential Utilization of Waste Sweetpotato Vines Hydrolysate as a New Source for Single Cell Oils Production by Trichosporon Fermentans. Bioresour Technol. 2013 May;135:622-9
  44. Yu F, Lee J, Jen N, Li X, Zhang Q, Tang R, Zhou Q, Kim ES, Hsiai TK. Elevated Electrochemical Impedance in the Endoluminal Regions with High Shear Stress: Implication for Assessing Lipid-Rich Atherosclerotic Lesions. Biosens Bioelectron. 2013 May 15;43:237-44
  45. Yan X, Lam KH, Li X, Chen R, Ren W, Ren X, Zhou Q, Shung KK. Lead-Free Intravascular Ultrasound Transducer Using Bzt-50bct Ceramics. IEEE Trans Ultrason Ferroelectr Freq Control. 2013 Jun;60(6):1272-6
  46. Yan X, Ji H, Lam KH, Chen R, Zheng F, Ren W, Zhou Q, Shung KK. Lead-Free Bnt Composite Film for High-Frequency Broadband Ultrasonic Transducer Applications. IEEE Trans Ultrason Ferroelectr Freq Control. 2013 Jul;60(7):1533-7
  47. Xie Z, Chen SL, Fabiilli ML, Fowlkes JB, Shung KK, Zhou Q, Carson PL, Wang X. Simultaneous Viewing of Individual Cells and Ambient Microvasculature Using Optical Absorption and Fluorescence Contrasts. Mol Imaging. 2013 Nov-Dec;12(8)
  48. Shih CC, Huang CC, Zhou Q, Shung KK. High-Resolution Acoustic-Radiation-Force-Impulse Imaging for Assessing Corneal Sclerosis. IEEE Trans Med Imaging.2013 Jul;32(7):1316-24
  49. Raphael DT, Li X, Park J, Chen R, Chabok H, Barukh A, Zhou Q, Elgazery M, Shung KK. 20 Mhz Forward-Imaging Single-Element Beam Steering with an Internal Rotating Variable-Angle Reflecting Surface: Wire Phantom and Ex Vivo Pilot Study. Ultrasonics. 2013 Feb;53(2):561-9
  50. Qiu W, Yu Y, Chabok HR, Liu C, Tsang FK, Zhou Q, Shung KK, Zheng H, Sun L. A Flexible Annular-Array Imaging Platform for Micro-Ultrasound. IEEE Trans Ultrason Ferroelectr Freq Control. 2013 Jan;60(1):178-86
  51. Qi W, Li R, Ma T, Li J, Kirk Shung K, Zhou Q, Chen Z. Resonant Acoustic Radiation Force Optical Coherence Elastography. Appl Phys Lett. 2013 Sep 2;103(10):103704
  52. Park J, Li X, Zhou Q, Shung KK. Combined Chirp Coded Tissue Harmonic and Fundamental Ultrasound Imaging for Intravascular Ultrasound: 20-60 Mhz Phantom and Ex Vivo Results. Ultrasonics. 2013 Feb;53(2):369-76
  53. Park J, Huang Y, Chen R, Lee J, Cummins TM, Zhou Q, Lien CL, Shung KK. Pulse Inversion Chirp Coded Tissue Harmonic Imaging (Pi-Cthi) of Zebrafish Heart Using High Frame Rate Ultrasound Biomicroscopy. Ann Biomed Eng. 2013 Jan;41(1):41-52
  54. Park J, Cummins TM, Harrison M, Lee J, Zhou Q, Lien CL, Shung KK. High Frequency Photoacoustic Imaging for in Vivo Visualizing Blood Flow of Zebrafish Heart. Opt Express. 2013 Jun 17;21(12):14636-42
  55. Maresca D, Renaud G, van Soest G, Li X, Zhou Q, Shung KK, de Jong N, van der Steen AF. Contrast-Enhanced Intravascular Ultrasound Pulse Sequences for Bandwidth-Limited Transducers. Ultrasound Med Biol. 2013 Apr;39(4):706-13
  56. Liu Y, Lam KH, Kirk Shung K, Li J, Zhou Q. Enhanced Piezoelectric Performance of Composite Sol-Gel Thick Films Evaluated Using Piezoresponse Force Microscopy. J Appl Phys. 2013 May 14;113(18):187205
  57. Liu C, Djuth FT, Zhou Q, Shung KK. Micromachining Techniques in Developing High-Frequency Piezoelectric Composite Ultrasonic Array Transducers. IEEE Trans Ultrason Ferroelectr Freq Control. 2013 Dec;60(12):2615-25
  58. Lin YH, Tung KL, Wang SH, Zhou Q, Shung KK. Distribution and Deposition of Organic Fouling on the Microfiltration Membrane Evaluated by High-Frequency Ultrasound. J Memb Sci. 2013 Apr 15;433:100-11
  59. Li J, Ma T, Jing J, Zhang J, Patel PM, Kirk Shung K, Zhou Q, Chen Z. Miniature Optical Coherence Tomography-Ultrasound Probe for Automatically Coregistered Three-Dimensional Intracoronary Imaging with Real-Time Display. J Biomed Opt. 2013 Oct;18(10):100502
  60. Lam KH, Ji HF, Zheng F, Ren W, Zhou Q, Shung KK. Development of Lead-Free Single-Element Ultrahigh Frequency (170-320mhz) Ultrasonic Transducers. Ultrasonics. 2013 Jul;53(5):1033-8
  61. Lam KH, Hsu HS, Li Y, Lee C, Lin A, Zhou Q, Kim ES, Shung KK. Ultrahigh Frequency Lensless Ultrasonic Transducers for Acoustic Tweezers Application. Biotechnol Bioeng. 2013 Mar;110(3):881-6
  62. Hwang JY, Lee NS, Lee C, Lam KH, Kim HH, Woo J, Lin MY, Kisler K, Choi H, Zhou Q, Chow RH, Shung KK. Investigating Contactless High Frequency Ultrasound Microbeam Stimulation for Determination of Invasion Potential of Breast Cancer Cells. Biotechnol Bioeng. 2013 Oct;110(10):2697-705
  63. Hsu HS, Benjauthrit V, Wei Q, Huang Y, Zhou Q, Shung KK. Silver Doped 0.9pmn-Pt-0.1pzt Composite Films for Very High Frequency Ultrasonic Transducer Applications. Appl Phys A Mater Sci Process. 2013 May 1;111(2):459-63
  64. Chen R, Paeng DG, Lam KH, Zhou Q, Shung KK, Matsuoka N, Humayun MS. In Vivo Sonothrombolysis of Ear Marginal Vein of Rabbits Monitored with High-Frequency Ultrasound Needle Transducer. J Med Biol Eng. 2013;33(1):103-10
  65. Zhang C, Maslov K, Hu S, Chen R, Zhou Q, Shung KK, Wang LV. Reflection-Mode Submicron-Resolution in Vivo Photoacoustic Microscopy. J Biomed Opt. 2012 Feb;17(2):020501
  66. Ye S, Yang R, Xiong J, Shung KK, Zhou Q, Li C, Ren Q. Label-Free Imaging of Zebrafish Larvae in Vivo by Photoacoustic Microscopy. Biomed Opt Express. 2012 Feb 1;3(2):360-5
  67. Yao DK, Chen R, Maslov K, Zhou Q, Wang LV. Optimal Ultraviolet Wavelength for in Vivo Photoacoustic Imaging of Cell Nuclei. J Biomed Opt. 2012 May;17(5):056004
  68. Yang JM, Favazza C, Chen R, Yao J, Cai X, Maslov K, Zhou Q, Shung KK, Wang LV. Simultaneous Functional Photoacoustic and Ultrasonic Endoscopy of Internal Organs in Vivo. Nat Med. 2012 Aug;18(8):1297-302
  69. Yang JM, Chen R, Favazza C, Yao J, Li C, Hu Z, Zhou Q, Shung KK, Wang LV. A 2.5-Mm Diameter Probe for Photoacoustic and Ultrasonic Endoscopy. Opt Express. 2012 Oct 8;20(21):23944-53
  70. Xi L, Grobmyer SR, Wu L, Chen R, Zhou G, Gutwein LG, Sun J, Liao W, Zhou Q, Xie H, Jiang H. Evaluation of Breast Tumor Margins in Vivo with Intraoperative Photoacoustic Imaging. Opt Express. 2012 Apr 9;20(8):8726-31
  71. Qiu W, Chen Y, Li X, Yu Y, Cheng WF, Tsang FK, Zhou Q, Shung KK, Dai J, Sun L. An Open System for Intravascular Ultrasound Imaging. IEEE Trans Ultrason Ferroelectr Freq Control. 2012 Oct;59(10):2201-9
  72. Qi W, Chen R, Chou L, Liu G, Zhang J, Zhou Q, Chen Z. Phase-Resolved Acoustic Radiation Force Optical Coherence Elastography. J Biomed Opt. 2012 Nov;17(11):110505
  73. Park J, Hu C, Li X, Zhou Q, Shung KK. Wideband Linear Power Amplifier for High-Frequency Ultrasonic Coded Excitation Imaging. IEEE Trans Ultrason Ferroelectr Freq Control. 2012 Apr;59(4):825-32
  74. Liu C, Zhou Q, Djuth FT, Shung KK. High-Frequency (>50 Mhz) Medical Ultrasound Linear Arrays Fabricated from Micromachined Bulk Pzt Materials. IEEE Trans Ultrason Ferroelectr Freq Control. 2012 Feb;59(2):315-8
  75. Liu C, Djuth F, Li X, Chen R, Zhou Q, Shung KK. Micromachined High Frequency Pmn-Pt/Epoxy 1-3 Composite Ultrasonic Annular Array. Ultrasonics. 2012 Apr;52(4):497-502
  76. Li X, Wei W,Zhou Q, Shung KK, Chen Z. Intravascular Photoacoustic Imaging at 35 and 80 Mhz. J Biomed Opt. 2012 Oct;17(10):106005
  77. Li J, Li X, Jing J, Mohar D, Raney A, Mahon S, Brenner M, Zhou Q, Patel P, Shung KK, Chen Z. Integrated Intravascular Optical Coherence Tomography (Oct) - Ultrasound (Us) Catheter for Characterization of Atherosclerotic Plaques in Vivo. Conf Proc IEEE Eng Med Biol Soc. 2012;2012:3175-8
  78. Hsu HS, Zheng F, Li Y, Lee C, Zhou Q, Kirk Shung K. Focused High Frequency Needle Transducer for Ultrasonic Imaging and Trapping. Appl Phys Lett. 2012 Jul 9;101(2):24105
  79. Hsu HS, Benjauthrit V, Zheng F, Chen R, Huang Y, Zhou Q, Shung KK. Pmn-Pt-Pzt Composite Films for High Frequency Ultrasonic Transducer Applications. Sens Actuators A Phys. 2012 Jun;179:121-4
  80. Chen R, Wu J, Ho Lam K, Yao L, Zhou Q, Tian J, Han P, Shung KK. Thermal-Independent Properties of Pin-Pmn-Pt Single-Crystal Linear-Array Ultrasonic Transducers. IEEE Trans Ultrason Ferroelectr Freq Control. 2012 Dec;59(12):2777-84
  81. Zhu BP, Guo WK, Shen GZ, Zhou Q, Shung KK. Structure and Electrical Properties of (111)-Oriented Pb(Mg1/3nb2/3)O3-Pbzro3-Pbtio3 Thin Film for Ultra-High-Frequency Transducer Applications. IEEE Trans Ultrason Ferroelectr Freq Control. 2011 Sep;58(9):1962-7
  82. Zhou Q, Lau S, Wu D, Shung KK. Piezoelectric Films for High Frequency Ultrasonic Transducers in Biomedical Applications. Prog Mater Sci. 2011 Feb;56(2):139-74
  83. Zhou D, Cheung KF, Chen Y, Lau ST, Zhou Q, Shung KK, Luo HS, Dai J, Chan HL. Fabrication and Performance of Endoscopic Ultrasound Radial Arrays Based on Pmn-Pt Single Crystal/Epoxy 1-3 Composite. IEEE Trans Ultrason Ferroelectr Freq Control. 2011 Feb;58(2):477-84
  84. Yin J, Li X, Jing J, Li J, Mukai D, Mahon S, Edris A, Hoang K, Shung KK, Brenner M, Narula J, Zhou Q, Chen Z. Novel Combined Miniature Optical Coherence Tomography Ultrasound Probe for in Vivo Intravascular Imaging. J Biomed Opt. 2011 Jun;16(6):060505
  85. Yang Y, Wang G, Wang B, Li Z, Jia X, Zhou Q, Zhao Y. Biosorption of Acid Black 172 and Congo Red from Aqueous Solution by Nonviable Penicillium Yw 01: Kinetic Study, Equilibrium Isotherm and Artificial Neural Network Modeling. Bioresour Technol. 2011 Jan;102(2):828-34
  86. Yang Y, Li X, Wang T, Kumavor PD, Aguirre A, Shung KK, Zhou Q, Sanders M, Brewer M, Zhu Q. Integrated Optical Coherence Tomography, Ultrasound and Photoacoustic Imaging for Ovarian Tissue Characterization. Biomed Opt Express. 2011 Sep 1;2(9):2551-61
  87. Wei W, Li X, Zhou Q, Shung KK, Chen Z. Integrated Ultrasound and Photoacoustic Probe for Co-Registered Intravascular Imaging. J Biomed Opt. 2011 Oct;16(10):106001
  88. Tsui PH, Huang CC, Zhou Q, Shung KK. Cataract Measurement by Estimating the Ultrasonic Statistical Parameter Using an Ultrasound Needle Transducer: An in Vitro Study. Physiol Meas. 2011 May;32(5):513-22
  89. Su Q, Zhu B, Lee JH, Bi Z, Shung K, Zhou Q, Takeuchi S, Park BH, Jia Q, Wang H. Self-Separated Pzt Thick Films with Bulk-Like Piezoelectric and Electromechanical Properties. J Mater Res. 2011 Jun 14;26(11):1431-5
  90. Shen ZY, Li JF, Chen R, Zhou Q, Shung KK. Microscale 1-3-Type (Na,K)Nbo(3)-Based Pb-Free Piezocomposites for High-Frequency Ultrasonic Transducer Applications. J Am Ceram Soc. 2011 May;94(5):1346-9
  91. Rao B, Maslov K, Danielli A, Chen R, Shung KK, Zhou Q, Wang LV. Real-Time Four-Dimensional Optical-Resolution Photoacoustic Microscopy with Au Nanoparticle-Assisted Subdiffraction-Limit Resolution. Opt Lett. 2011 Apr 1;36(7):1137-9
  92. Lin H, Wang B, Zhuang R, Zhou Q, Zhao Y. Artificial Construction and Characterization of a Fungal Consortium That Produces Cellulolytic Enzyme System with Strong Wheat Straw Saccharification. Bioresour Technol. 2011 Nov;102(22):10569-76
  93. Li X, Wu W, Chung Y, Shih WY, Shih WH, Zhou Q, Shung KK. 80-Mhz Intravascular Ultrasound Transducer Using Pmn-Pt Free-Standing Film. IEEE Trans Ultrason Ferroelectr Freq Control. 2011 Nov;58(11):2281-8
  94. Lau ST, Ji HF, Li X, Ren W, Zhou Q, Shung KK. Knn/Bnt Composite Lead-Free Films for High-Frequency Ultrasonic Transducer Applications. IEEE Trans Ultrason Ferroelectr Freq Control. 2011 Jan;58(1):249-54
  95. Ji H, Ren W, Wang L, Shi P, Chen X, Wu X, Yao X, Lau ST, Zhou Q, Shung KK. Structure and Electrical Properties of Na0.5bi0.5tio3 Ferroelectric Thick Films Derived from a Polymer Modified Sol-Gel Method. IEEE Trans Ultrason Ferroelectr Freq Control. 2011 Oct;58(10):2042-9
  96. Choi H, Li X, Lau ST, Hu C, Zhou Q, Shung KK. Development of Integrated Preamplifier for High-Frequency Ultrasonic Transducers and Low-Power Handheld Receiver. IEEE Trans Ultrason Ferroelectr Freq Control. 2011 Dec;58(12):2646-58
  97. Chiang HK, Zhou Q, Mandell MS, Tsou MY, Lin SP, Shung KK, Ting CK. Eyes in the Needle: Novel Epidural Needle with Embedded High-Frequency Ultrasound Transducer--Epidural Access in Porcine Model. Anesthesiology. 2011 Jun;114(6):1320-4
  98. Chabok HR, Zhou Q, Alagha S, Tian J, Han P, Shung KK. Thickness Dependent Characteristics of High Permittivity Pmn-0.32pt Single Crystal for High Frequency Medical Imaging Applications. Ferroelectrics. 2011;422(1):70-6
  99. Zhu J, Lee C, Kim ES, Wu D, Hu C, Zhou Q, Shung KK, Wang G, Yu H. High-Overtone Self-Focusing Acoustic Transducers for High-Frequency Ultrasonic Doppler. Ultrasonics. 2010 May;50(6):544-7
  100. Zhu B, Han J, Shi J, Shung KK, Wei Q, Huang Y, Kosec M, Zhou Q. Lift-Off Pmn-Pt Thick Film for High Frequency Ultrasonic Biomicroscopy. J Am Ceram Soc. 2010 Oct;93(10):2929-31
  101. Zhou Q, Wu D, Liu C, Zhu B, Djuth F, Shung K. Micro-Machined High-Frequency (80 Mhz) Pzt Thick Film Linear Arrays. IEEE Trans Ultrason Ferroelectr Freq Control. 2010 Oct;57(10):2213-20
  102. Yin J, Yang HC, Li X, Zhang J, Zhou Q, Hu C, Shung KK, Chen Z. Integrated Intravascular Optical Coherence Tomography Ultrasound Imaging System. J Biomed Opt. 2010 Jan-Feb;15(1):010512
  103. Yao DK, Maslov K, Shung KK, Zhou Q, Wang LV. In Vivo Label-Free Photoacoustic Microscopy of Cell Nuclei by Excitation of DNA and Rna. Opt Lett. 2010 Dec 15;35(24):4139-41
  104. Yang HC, Yin J, Hu C, Cannata J, Zhou Q, Zhang J, Chen Z, Shung KK. A Dual-Modality Probe Utilizing Intravascular Ultrasound and Optical Coherence Tomography for Intravascular Imaging Applications. IEEE Trans Ultrason Ferroelectr Freq Control. 2010 Dec;57(12):2839-43
  105. Wang J, Liu T, Jiao S, Chen R, Zhou Q, Shung KK, Wang LV, Zhang HF. Saturation Effect in Functional Photoacoustic Imaging. J Biomed Opt. 2010 Mar-Apr;15(2):021317
  106. Sun P, Wang G, Wu D, Zhu B, Hu C, Liu C, Djuth FT, Zhou Q, Shung KK. High Frequency Pmn-Pt 1-3 Composite Transducer for Ultrasonic Imaging Application. Ferroelectrics. 2010;408(1):120-8
  107. Matsuoka N, Paeng DG, Chen R, Ameri H, Abdallah W, Zhou Q, Fawzi A, Shung KK, Humayun M. Ultrasonic Doppler Measurements of Blood Flow Velocity of Rabbit Retinal Vessels Using a 45-Mhz Needle Transducer. Graefes Arch Clin Exp Ophthalmol. 2010 May;248(5):675-80
  108. Li X, Yin J, Hu C, Zhou Q, Shung KK, Chen Z. High-Resolution Coregistered Intravascular Imaging with Integrated Ultrasound and Optical Coherence Tomography Probe. Appl Phys Lett. 2010 Sep 27;97(13):133702
  109. Jiao S, Jiang M, Hu J, Fawzi A, Zhou Q, Shung KK, Puliafito CA, Zhang HF. Photoacoustic Ophthalmoscopy for in Vivo Retinal Imaging. Opt Express. 2010 Feb 15;18(4):3967-72
  110. Zhou Q, Cha JH, Huang Y, Zhang R, Cao W, Shung KK. Alumina/Epoxy Nanocomposite Matching Layers for High-Frequency Ultrasound Transducer Application. IEEE Trans Ultrason Ferroelectr Freq Control. 2009 Jan;56(1):213-9
  111. Yang JM, Maslov K, Yang HC, Zhou Q, Shung KK, Wang LV. Photoacoustic Endoscopy. Opt Lett. 2009 May 15;34(10):1591-3
  112. Wu DW, Zhou Q, Geng X, Liu CG, Djuth F, Shung KK. Very High Frequency (Beyond 100 Mhz) Pzt Kerfless Linear Arrays. IEEE Trans Ultrason Ferroelectr Freq Control. 2009 Oct;56(10):2304-10
  113. Wu D, Zhou Q, Shung KK, Bharadwaja SN, Zhang D, Zheng H. Dielectric and Piezoelectric Properties of Pzt Composite Thick Films with Variable Solution to Powder Ratios. J Am Ceram Soc. 2009 May 8;92(6):1276-9
  114. Sun P, Zhou Q, Zhu B, Wu D, Hu C, Cannata JM, Tian J, Han P, Wang G, Shung KK. Design and Fabrication of Pin-Pmn-Pt Single-Crystal High-Frequency Ultrasound Transducers. IEEE Trans Ultrason Ferroelectr Freq Control. 2009 Dec;56(12):2760-3
  115. Sun P, Zhang Y, Yu F, Parks E, Lyman A, Wu Q, Ai L, Hu CH, Zhou Q, Shung K, Lien CL, Hsiai TK. Micro-Electrocardiograms to Study Post-Ventricular Amputation of Zebrafish Heart. Ann Biomed Eng. 2009 May;37(5):890-901
  116. Huang CC, Chen R, Tsui PH, Zhou Q, Humayun MS, Shung KK. Measurements of Attenuation Coefficient for Evaluating the Hardness of a Cataract Lens by a High-Frequency Ultrasonic Needle Transducer. Phys Med Biol. 2009 Oct 7;54(19):5981-94
  117. Zhou Q, Wu D, Jin J, Hu CH, Xu X, Williams J, Cannata JM, Lim L, Shung KK. Design and Fabrication of Pzn-7%Pt Single Crystal High Frequency Angled Needle Ultrasound Transducers. IEEE Trans Ultrason Ferroelectr Freq Control. 2008;55(6):1394-9
  118. Lau ST, Shao LY, Chan HL, Tam HY, Hu CH, Kim HH, Liu R, Zhou Q, Shung KK. Characterization of a 40-Mhz Focused Transducer with a Fiber Grating Laser Hydrophone. IEEE Trans Ultrason Ferroelectr Freq Control. 2008 Dec;55(12):2714-8
  119. Hu CH, Zhou Q, Shung KK. Design and Implementation of High Frequency Ultrasound Pulsed-Wave Doppler Using Fpga. IEEE Trans Ultrason Ferroelectr Freq Control. 2008 Sep;55(9):2109-11
  120. Zhou Q, Xu X, Gottlieb EJ, Sun L, Cannata JM, Ameri H, Humayun MS, Han P, Shung KK. Pmn-Pt Single Crystal, High-Frequency Ultrasonic Needle Transducers for Pulsed-Wave Doppler Application. IEEE Trans Ultrason Ferroelectr Freq Control. 2007 Mar;54(3):668-75
  121. Zhang R, Cao W, Zhou Q, Cha JH, Shung KK, Huang Y. Acoustic Properties of Alumina Colloidal/Polymer Nano-Composite Film on Silicon. IEEE Trans Ultrason Ferroelectr Freq Control. 2007 Mar;54(3):467-9
  122. Huang CC, Zhou Q, Ameri H, Wu DW, Sun L, Wang SH, Humayun MS, Shung KK. Determining the Acoustic Properties of the Lens Using a High-Frequency Ultrasonic Needle Transducer. Ultrasound Med Biol. 2007 Dec;33(12):1971-7
  123. Hu CH, Liu R, Zhou Q, Yen J, Kirk Shung K. Coded Excitation Using Biphase-Coded Pulse with Mismatched Filters for High-Frequency Ultrasound Imaging. Ultrasonics. 2006 Jul;44(3):330-6
  124. Cannata JM, Williams JA, Zhou Q, Ritter TA, Shung KK. Development of a 35-Mhz Piezo-Composite Ultrasound Array for Medical Imaging. IEEE Trans Ultrason Ferroelectr Freq Control. 2006 Jan;53(1):224-36
  125. Zhou Q, Cannata JM, Meyer RJ, Jr., van Tol DJ, Tadigadapa S, Hughes WJ, Shung KK, Trolier-McKinstry S. Fabrication and Characterization of Micromachined High-Frequency Tonpilz Transducers Derived by Pzt Thick Films. IEEE Trans Ultrason Ferroelectr Freq Control. 2005 Mar;52(3):350-7
  126. Zhou Q, Cannata JM, Guo H, Huang C, Marmarelis VZ, Shung KK. Half-Thickness Inversion Layer High-Frequency Ultrasonic Transducers Using Linbo3 Single Crystal. IEEE Trans Ultrason Ferroelectr Freq Control. 2005 Jan;52(1):127-33
  127. Huang C, Marmarelis VZ, Zhou Q, Shung KK. An Analytical Model of Multilayer Ultrasonic Transducers with an Inversion Layer. IEEE Trans Ultrason Ferroelectr Freq Control. 2005 Mar;52(3):469-79
  128. Guo H, Cannata JM, Zhou Q, Shung KK. Design and Fabrication of Broadband Graded Ultrasonic Transducers with Rectangular Kerfs. IEEE Trans Ultrason Ferroelectr Freq Control. 2005 Nov;52(11):2096-102