Typically needed for serpiginous and to spare steroids
Alkylating agents (eg cyclophosphamide and chlorambucil) and antimetabolites
Limited data but appears effective. Last resort and thorough discussion with patient
Biologicals (eg interferon alpha-2a)
Prognosis and Future Directions
Serpiginous choroidopathy is a rare inflammatory condition of outer retina and choroid with poor visual prognosis due to permanent retinal damage
Thorough history and exam are necessary to distinguish it from other “white dot syndromes” and infectious etiologies such as tuberculosis, as these require different management and depending on the etiology may have better prognosis
Close monitoring with fundus auto-fluorescence and OCT are necessary. Fluorescein angiography is also important to monitor for CNV. Management focuses on catching and limiting recurrent flares as well as preventing recurrence
Research is ongoing about the exact etiology of serpiginous choroidopathy
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Hossein Ameri, MD, PhD, Assistant Professor of Clinical Ophthalmology, firstname.lastname@example.org