USC Roski Eye Institute Helps Blind Patient Regain Sight with Two Retinal Implants

Terry Byland and his wife Sue, just before his surgery to implant an Argus II prosthetic device in his left eye.When USC Roski Eye Institute patient Terry Byland fully lost his sight to retinitis pigmentosa at age 45, he never could have imagined what his future had in store. Byland recently became the first person in the world to have to retinal prostheses implanted – one in each eye – restoring some sight and much-needed independence.

“I just can’t get over what I can see, and all the things I’ve seen so far,” Byland said.

The 66-year-old Riverside resident began his journey toward regaining his sight when he participated in a clinical trial for the original retinal prostheses, the Argus I, between 2004 and 2010. The 16-electrode artificial retina was implanted in his right eye on June 23, 2004.

Participating in the initial trial gave Byland new purpose after struggling with not only retiring early and giving up the job he loved, but also losing out on getting to watch his children grow up.

“Terry is a true pioneer,” said Mark Humayun, M.D., Ph.D., co-inventor of the device, who holds joint appointments at the Keck School of Medicine of USC and the USC Viterbi School of Engineering. “His work with the first-generation implant helped our team develop the FDA-approved Argus II. For him to enjoy the benefit of this smaller, better device is gratifying.”

On June 22, 2015, Byland received the new 60-electrode Argus II implant by Lisa Olmos de Koo, M.D. at the USC Roski Eye Institute. The Argus II is equipped with software that can be updated as new image processing technology becomes available, allowing Byland to have new features introduced to continually improve his sight.

Combining Medicine and Engineering

The Argus II is revolutionary in that it helps patients identify large letters as well as locate objects using a small video camera, which is mounted to a pair of eyeglasses. The video processing unit then transforms the images picked up by the camera into electronic signals that are wirelessly transmitted to the implant. The prosthesis stimulates visual neurons that send the signals through the optic nerve to the brain, which are interpreted as a visual image.

“The prosthesis allows more independence. And the more independent you are, the happier you are,” said Byland.

The Argus II is the groundbreaking success of a close collaboration between USC Roski Eye Institute, Keck School of Medicine of USC, and USC Viterbi School of Engineering. The device is designed to help patients who have suffered blindness as a result of an inherited retinal degenerative disease called retinitis pigmentosa.

Contact an Innovative Ophthalmology Team

The Argus II is available to qualifying patients at the Keck Medical Center of USC. It is important to receive a thorough eye exam from a professional optometrist or ophthalmologist to catch vision problems and get effective treatment. Please do not wait to make an appointment with a skilled ophthalmologist at USC Roski Eye Institute for a comprehensive eye exam using the most state-of-the-art technology available.

Help support our research and innovation by making a tax-deductible gift by contacting Rebecca Melville, senior director of development, at 323.442.5396 or via email at Rebecca.Melville@med.usc.edu today!


PROSE Treatment Brings Relief to Cancer Survivor

USC Eye PROSE Treatment
“I had lost all hope until I came to the USC Roski Eye Institute. I’m excited about the PROSE treatment because it will take care of my pain so that I can live a normal life.” – Nicole Schultz, USC Roski Eye Institute patient

Nicole Schultz, a two-time cancer survivor, has been suffering from the devastating effects of a condition known as ocular graft-versus-host disease (GvHD).

Medical and Ocular History

Schultz was diagnosed with ocular GvHD following her second bone marrow transplant, which she received during her cancer treatment. Serious complications can arise in patients with GvHD, when donor cells from transplants attack connective tissue of the patient or host. For Schultz, GvHD manifested in her eyes, which were no longer able to produce tears and resulted in painful flare-ups. For years she sought treatment for dry eye, visiting many doctors, who prescribed various eye drops and even punctal plugs to increase tears and moisture in her eyes. Schultz’s life changed dramatically, since she was required to administer drops multiple times a day to diminish the pain she experienced. She says she was on the verge of giving up hope when it was suggested to visit the USC Roski Eye Institute to try a unique contact lens treatment option known as prosthetic replacement of the ocular surface ecosystem (PROSE).

Gloria Chiu, OD, FAAO Assistant Professor of Clinical Ophthalmology and Chief Optometrist Specialty: PROSE and Specialty Contact Lens
Gloria Chiu, OD, FAAO, FSLS, Assistant Professor of Clinical Ophthalmology and Chief Optometrist
Specialty: PROSE and Specialty Contact Lens

After meeting Schultz for the first time, Gloria Chiu, OD, FAAO, FSLS, who is trained in PROSE treatment, immediately knew that she could help relieve Schultz’s symptoms.

PROSE treatment, a non-surgical procedure, is offered to patients who suffer from serious corneal conditions and ocular surface diseases. PROSE therapy reduces symptoms, supports healing and improves vision through the use of a prosthetic scleral device that is tailored for each individual. Schultz is also using non-preserved artificial tears with PROSE therapy to enhance comfort and fit.

Recent studies have demonstrated that patients who received this pioneering treatment experienced a notable improvement in their quality of vision and quality of life as a result.

The USC Roski Eye Institute is the third of 12 sites in the nation to offer PROSE technology to our patients. Chiu is one of only two West Coast eye care providers to offer PROSE treatment.


“It is a privilege to be able to provide Nicole with a treatment that can quite simply change her life. These custom devices help to improve her vision, comfort and assist in the healing of her ocular surface,” says Chiu.

For more information on PROSE treatment, please visit eye.keckmedicine.org/PROSE

Join the USC Roski Eye Institute in its quest to preserve, protect and restore the gift of sight by making your tax-deductible donation today. Thank you for your support! GIVETO.USC.EDU/EYE

Next, read about Ophthalmic Services Provided to Special Olympic Athletes

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